Protein Alignment Cyp6a19 and Cyp3a62

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 163/506 - (32%)
• Similarity: 238/506 - (47%)
• Gaps: 96/506 - (18%)

  Fly    36 PNIPLGNTGELWRTMPLAGILKRTYLKFRKQTDG-------------PFA--------------- 72
            |||.|    |.|  |.||.||...|| :...|.|             ||.
  Rat     5 PNISL----ETW--MLLATILVLLYL-YGTSTHGNFKKLGISGPKPLPFVGNILAYRHGFWEFDR 62

  Fly    73 ----------GFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDR------GVYHNEKDDPLTNNLA 120
                      |||......:.|||.|.:||||::: :..|.:|      |:        |...:.
  Rat    63 HCHKKYGDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAGI--------LKKAIT 119

  Fly   121 TIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDV 185
            ..|.::||.||..|:.||||.|:|.||..:....|.:::.|..: :.....:.:.||...::.||
  Rat   120 LSEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHE-AEKGNPITMKDIFGAYSMDV 183

  Fly   186 IGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGM--PKLAVKLGFQFLLP----- 243
            |...:||:..:||.:|:..|||.            :..||.|..  |.....:.|.||.|
  Rat   184 ITGTSFGVNVDSLNNPQNPFVQK------------VKKLLKFNFLDPFFLSVILFPFLTPVFEAF 236

  Fly   244 -------SVQKFYMKIVQDTIDYRMKRKV-TRNDFMDTLIDMKQQYDKGDKEN--GLAFNEVAAQ 298
                   .|.||:...|:...:.||:.|| .|.||:..:|:.:   ..||||:  ||...|:.||
  Rat   237 DITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMINSQ---SSGDKESHQGLTDVEIVAQ 298

  Fly   299 AFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINE 363
            :..|..||:|..|:.:.|.||.||.:.|:|.||:.|||:.|.. ...:.||.:.::.|::.|:||
  Rat   299 SIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALPN-KAPVTYDVLVEMEYLDMVLNE 362

  Fly   364 SLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVK 428
            :||..||...|.|:..|..:.:.  .||..||.|:|.|..:|.||:.:||||:|.||||.::...
  Rat   363 TLRLFPVGGRLERVCKKDVEING--VFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQD 425

  Fly   429 KRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMK 479
            ......:||||.|||||||:||..|.:.|.|..::.||.|.|..:|.:|:|
  Rat   426 SINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGLCKETQIPLK 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	163/506 (32%)
Cyp3a62	NP_001019403.1	p450	39..491	CDD:278495	148/465 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.770