Protein Alignment Cyp6a19 and Cyp4b1

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 558
• Identity: 136/558 - (24%)
• Similarity: 231/558 - (41%)
• Gaps: 137/558 - (24%)

  Fly     5 LGLVVGVLTLVAWWVLQNYTYWKRR--------GIPHDPPNIPLGNTGELWRTMPLAGILKRTYL 61
            |||...|:.|:. .||:..:...||        ..|..|.:...|:..|:.:|..|..::..|
Mouse    13 LGLWASVVILMV-TVLKLLSLLFRRQKLARALDSFPGPPKHWLFGHALEIQKTGGLDKVVTWT-- 74

  Fly    62 KFRKQTDGPFAGFYLYAMKYIVITDV---DFVKTVLIRDFDKFHDRGVYHNEKDDP--------- 114
                 ...|:| ..|:..::||..::   |:.|.|        :.||       ||
Mouse    75 -----EQFPYA-HPLWLGQFIVFLNIYEPDYAKAV--------YSRG-------DPKAAYVYDFF 118

  Fly   115 ---LTNNLATIEGQKWKNLRQKLTHTFTSAKMK---SMFSTVLNVGDEMIRV-VD--EKISSSSQ 170
               :...|..:||.||...|:.||..|....:|   ::|:       |..|| :|  ||.:|.::
Mouse   119 LQWIGKGLLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFA-------ESTRVMLDKWEKKASENK 176

  Fly   171 TLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLV---DLLIFGMPKL 232
            :.::...|.....|.:..|.||               .|.|.|....:.:.:   ||.:....::
Mouse   177 SFDIFCDVGHMALDTLMKCTFG---------------KGDSGLSHSDNSYYLAVSDLTLLMQQRI 226

  Fly   233 AVKLGFQF-------LLPSVQKFY--MKIVQDTIDY--RMKRKVTRN-------------DFMDT 273
            .   .||:       |.|..::|.  .:|..|..|:  |.::...::             ||:|.
Mouse   227 D---SFQYHNDFIYWLTPHGRRFLRACQIAHDHTDHVIRQRKAALQDEKEQKKLQERRHLDFLDI 288

  Fly   274 LIDMKQQYDKGDKENGLAFN--EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEID 336
            |:..:.       |:|:..:  ::.|:...|...|.:..::.:.:.||.:|.....|.:.|.|:.
Mouse   289 LLGARD-------ESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVR 346

  Fly   337 SVL-ERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIE-----AGT 395
            .:| :|  ...::|.:..:.|:...:.|..|.:|.|..:.|      |.|.|..|::     ||:
Mouse   347 EILGDR--DSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYR------QLSKPVTFVDGRSLPAGS 403

  Fly   396 GVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRF--GRMQVIIG 458
            .:.:....:|.:...:|:||.|.|.||..|.:..|...||:||.||||||||.:|  ..|:|:..
Mouse   404 LISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTA 468

  Fly   459 LALLIHNFRFELHP-KTPVPMKYTINNLLLGSEGGIHL 495
            |.||    |||..| .:.:|:|  :..|:|.|:.||||
Mouse   469 LCLL----RFEFSPDPSKIPIK--VPQLILRSKNGIHL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	125/521 (24%)
Cyp4b1	NP_031849.1	p450	47..500	CDD:278495	125/521 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900