Protein Alignment Cyp6a19 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 448
• Identity: 119/448 - (26%)
• Similarity: 197/448 - (43%)
• Gaps: 64/448 - (14%)

  Fly    82 IVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDP-LTNNLATIEGQKWKNLRQKLTHTFTSAKMKS 145
            :::.|.|:||.||.|...|  ..|:|  :...| :...|..:.|:||...|:.||..|....:|.
Mouse    94 VLLYDPDYVKVVLGRSDPK--ASGIY--QFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKP 154

  Fly   146 MFSTVLNVGDEMIRVVD--EKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQM 208
            .   |..:.|.:..::|  ||:......||:...||..|.|.:..|||..:.:...|..::....
Mouse   155 Y---VKIMADSVNIMLDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTK 216

  Fly   209 GYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS------------------VQKFYMKIVQD 255
            ....|.        :|..|.:.....|....:.:.|                  |.|.....:|:
Mouse   217 AVEDLN--------NLTFFRLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQN 273

  Fly   256 TIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYE 320
            ..:.:..||....||:|.|:     :.:.:..|.|:..::.|:...|...|.:..::.:.:..|.
Mouse   274 EEELQKARKKRHLDFLDILL-----FARMEDRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFYA 333

  Fly   321 LACNQDVQDKLRAEIDSVLERYNG-KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQ- 383
            ||.:.:.|.:.|.|:.|:|.  :| .:.:|.:..:.|....|.|:||.:|.|..::|..:.|..
Mouse   334 LATHPEHQQRCREEVQSILG--DGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTF 396

  Fly   384 ---HSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNC 445
               .|.||     |....:|..|:||:|.|:|.|:.|.|.||..:  ....:.|:|||..|.|||
Mouse   397 PDGRSIPK-----GITATISIYGLHHNPRFWPNPKVFDPSRFAPD--SSHHSHAYLPFSGGSRNC 454

  Fly   446 IGLRFGRMQVIIGLALLIHNFRFELHP---KTPVPMKYTINNLLLGSEGGIHLNITKV 500
            ||.:|...::.:.:||.:  .||||.|   :.|||    |..|:|.|:.||||.:.|:
Mouse   455 IGKQFAMNELKVAVALTL--LRFELLPDPTRIPVP----IARLVLKSKNGIHLCLKKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	115/440 (26%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	117/442 (26%)