Protein Alignment Cyp6a19 and Cyp3a16

DIOPT Version :9

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 539
• Identity: 161/539 - (29%)
• Similarity: 270/539 - (50%)
• Gaps: 77/539 - (14%)

  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTY-------WKRRGIPHDPPNIPLGNTGELWRTMPLAGILK- 57
            |.:...|.:..|.|:|..::..|.|       :|::|||...|...||.....::     |:.|
Mouse     1 MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYK-----GLWKF 60

  Fly    58 --RTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDR------GVYHNEKDD 113
              ..|.|:.| |.|.|.|    .:...||||.:.:|.||::: |..|.:|      |:
Mouse    61 DMECYEKYGK-TWGLFDG----QIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGI------- 113

  Fly   114 PLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIV 178
             ::.:::..:.::||..|..|:.||||..:|.||..:...||.:::.:.:: :...:.:.|.|::
Mouse   114 -MSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQE-AEKGKPVAVKDVL 176

  Fly   179 SRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLP 243
            ..::.|||....||:..:||.:|:..||:.....||         ...|....|:|.| |.||.|
Mouse   177 GAYSMDVIISTTFGVNIDSLNNPEDPFVENAKKVLR---------FDYFDPLSLSVAL-FPFLTP 231

  Fly   244 -------------SVQ---KFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKG-DKENGLA 291
                         |::   ||..::.::.:|.:.|.:|      |.:..|.:.|:|. ||::..|
Mouse   232 IYEMLNICMFPKDSIEFFKKFVDRMTENRLDSKQKHRV------DFIYLMMEAYNKSKDKDSHKA 290

  Fly   292 FN--EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDL 354
            .:  |:.||:.:|..||:|..|:.:.||:|.||.:.|:|.||:.|||..|.. .....||::..:
Mouse   291 LSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPN-KAPPTYDTVMAM 354

  Fly   355 FYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIP 419
            .|::.|:||:||.:|:...|.|:..|..:.:.  .:|..|:.|::.:..:||||:.:||||:|.|
Mouse   355 EYLDMVLNETLRLYPITNRLQRVCKKDVEING--IYIPKGSTVIIPSYVLHHDPQHWPEPEEFQP 417

  Fly   420 ERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINN 484
            |||.:|.........:||||.|||||||:||..|.:.:.|..::.||.|:...:|.:|:|.: ..
Mouse   418 ERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLS-RE 481

  Fly   485 LLLGSEGGIHLNITKVVRD 503
            |||.....|.|.:  |.||
Mouse   482 LLLQPVKPIVLKV--VPRD 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	147/491 (30%)
Cyp3a16	NP_031846.2	p450	39..494	CDD:278495	148/493 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720