Protein Alignment Cyp6a19 and Cyp4aa1

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_313368.6
• Gene: Cyp4aa1 / 1274272
• VectorBaseID: AGAMI1_007136
• Length: 498
• Species: Anopheles gambiae
• Alignment Length: 503
• Identity: 125/503 - (24%)
• Similarity: 217/503 - (43%)
• Gaps: 88/503 - (17%)

  Fly    35 PPNIP-LGNTGELWRTMPLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDF 98
            |.:.| :||..::.|...:...:.:.|..:     ||.|..:::.....|:.|.:.:|.:|  ..
Mosquito    47 PKSYPIIGNCLDIARKDLITREMAQAYKNY-----GPLARVWIFVFPMFVVFDPNDLKVIL--SS 104

  Fly    99 DKFHDRGVYHNEKDDPLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDE 163
            .|..::.:::....:.|...|.|..|.||.:.|:.:..:|..|.::....|..:....:|    :
Mosquito   105 KKHTNKSMFYKLLHNFLGRGLITSSGHKWSSHRKLIQPSFNIAILEKFIDTFTDSASFLI----D 165

  Fly   164 KISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERR--------HGW 220
            |:......|.||:.|:....|::.....|:...|: |.|    :|..|..|:.:        |.|
Mosquito   166 KLPKEETVLNVTEYVNNCVLDILNEAVLGVPVKSV-DKK----EMEQSPFRQGKVVAPYRITHPW 225

  Fly   221 LVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDK-- 283
            |                   |..|:.|     :.|.....:.:|...:||...:|..:::..|
Mosquito   226 L-------------------LFNSIYK-----LTDAATAELNQKKQLDDFSRKMIRRRREILKTL 266

  Fly   284 --GDKENGLAF-------------NEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRA 333
              .|:...|.|             :::..:|..|.|||.::....:.|||:.||.:||.|.|...
Mosquito   267 SPSDRRCLLDFMIEISNENPDFTEDDIIDEACTFMLAGQDSVGAAVAFTLFLLARHQDQQAKCYE 331

  Fly   334 EIDSVLERYNG-----KLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEA 393
            ||    ||:.|     ....:.:::|.::|..|.||||.:|.|..:||...:..:..  ||.:..
Mosquito   332 EI----ERHIGTDCSKPPSAEGIRELRHLEACIKESLRLYPSVPLMARKIGEDVRVG--KYNLPT 390

  Fly   394 GTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIG 458
            ||.:::.....|.....||:||:|.||||.:....:.| .|||||.||||||||.:|..:::...
Mosquito   391 GTEIMILPYATHRLEHIYPDPERFDPERFGDGAPHQNP-YAFLPFSAGPRNCIGYKFAYIEMKTV 454

  Fly   459 LALLIHNFRFELHPKTPVPMKYTIN---NLLLGSEGGIHLNIT--KVV 501
            :|.::.||..     :|.|.|..:.   .:.|.:.||:.:.:|  |||
Mosquito   455 IARVLQNFHL-----SPAPGKEEVQPIFRMTLRARGGLWVKMTPRKVV 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	115/459 (25%)
Cyp4aa1	XP_313368.6	None