Protein Alignment Cyp6a19 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 127/518 - (24%)
• Similarity: 217/518 - (41%)
• Gaps: 85/518 - (16%)

  Fly     1 MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDP-PNIPLGNTGELWRTMPLAGILKRTYLKFR 64
            :.|::|.||..|...|:   ..|.:.|...||..| .:..||:...|.:......::...:|.:
 Frog    18 LLIIIGAVVAFLAYCAY---IKYMHLKYDDIPGPPRDSFLLGHIPTLSKAEENYSVVHDLFLHW- 78

  Fly    65 KQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLT-NNLATIEGQK-- 126
            .:..||.....:.....|..|..:.||..|:.  .|:         ..||.| |.|..:.|::
 Frog    79 AEIYGPVFKINILHRVMIYSTSPESVKECLMS--SKY---------PKDPYTYNQLFNLFGKRFL 132

  Fly   127 ------------WKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVS 179
                        |.:.|:.:...|::..:|.|........::|:..::|| :...|.:.:..|::
 Frog   133 GKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEK-ADGHQEVSMHSIIN 196

  Fly   180 RFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS 244
            |.|.|||...|||:....:...|.:|..             .:..::.||.:....       |.
 Frog   197 RVTLDVITKVAFGMDLGLVEGNKTDFPN-------------AISKVLTGMMRYMQN-------PY 241

  Fly   245 VQKF-----YMKIVQDTIDYRMK---------RKVTRN------DFMDTLIDMKQQYDKGDKENG 289
            :|.|     :::.||::.|...|         :|..:|      |.:..::..      .:.||.
 Frog   242 MQYFPKHWAFVREVQESADLLRKTGKECISQRKKAMQNGEELPKDILTKILQC------AELENA 300

  Fly   290 LAFNEVAAQAFV-FFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQD 353
            |. :|:....|: ||:||.|..:..:.||:.||....::..|||.|:|.|: .:...:.||.:|:
 Frog   301 LD-DEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVI-GFKRDISYDDIQN 363

  Fly   354 LFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFI 418
            |.||.:|:.||||.:|.....:|...:.......|  |..|..:..:|..:....:|:.:|.||.
 Frog   364 LNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIK--IPGGVSITFNTYVMGRMEKFFQDPCKFD 426

  Fly   419 PERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYT 481
            ||||....||  |...:.||..|||:|:|..|.:::..:.|:.||..|.|||.|.....:|.|
 Frog   427 PERFHPAAVK--PYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFELVPGQSFGIKDT 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	112/451 (25%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	113/461 (25%)