Protein Alignment Cyp6a19 and cyp4b1.3

DIOPT Version :10

• Sequence 1: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: XP_002931492.1
• Gene: cyp4b1.3 / 100487918
• XenbaseID: XB-GENE-980014
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 555
• Identity: 138/555 - (24%)
• Similarity: 222/555 - (40%)
• Gaps: 123/555 - (22%)

  Fly     2 AILLGLVVGVL----TLVAWW----VLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKR 58
            |.||.|::.:|    ..:.|.    .|||:        |..|.:...||..:
 Frog    25 AALLCLILLLLKACGLFIRWKSLKDALQNF--------PGPPKHWLYGNANQ------------- 68

  Fly    59 TYLKFRKQTDG-PFAGFYLYAMKY--------------IVITDVDFVKTVLIRDFDKFHDRGVYH 108
                ||  .|| ......|:|.||              :|||:.::.|....|
 Frog    69 ----FR--NDGTDMDRILLWANKYPKAFPLWVGQFFASLVITNPEYAKAAFAR------------ 115

  Fly   109 NEKDDPLT------------NNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVV 161
               .||.|            ..|..:.|..|...|:.||..|....:|.....:    .:..:|:
 Frog   116 ---SDPKTPTGYDFLIPWIGKGLLVLSGDTWFQHRRLLTPGFHYDVLKPYAKLI----SDSTKVM 173

  Fly   162 DEK---ISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGY--SALRERR---- 217
            .:|   .|:..:.:|:...||..|.|.|..|||....|...|....:.:..|  |.|...|
 Frog   174 LDKWVPFSNKGEPVELFHHVSLMTLDSIMKCAFSYHSNCQTDNDNSYTKAVYDLSYLTHHRARTF 238

  Fly   218 ------------HGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKVTRNDF 270
                        ||:|.        :.|.::..|. ...|.|....::|:..::...::....||
 Frog   239 PYHNNLIYYLSPHGFLF--------RKACRIAHQH-TDKVIKQRKTLLQNKEEFEKVKQKRHPDF 294

  Fly   271 MDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEI 335
            :|.|:..:.:..|     ||:..::.|:...|...|.:..::.:.:.||.:|...:.|.|.|.||
 Frog   295 LDILLCARDENGK-----GLSDEDLRAEVDTFMFEGHDTTASGISWILYCMAKYPEHQQKCREEI 354

  Fly   336 DSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVS 400
            ..||.. ....|::.:..:.|....|.||||.:|.|..::|...||...|:.: .:.||:.:.::
 Frog   355 RDVLGE-KESFEWEDLNKIPYTTMCIKESLRLYPPVPAVSRELNKPITFSDGR-SLPAGSVIFIN 417

  Fly   401 TLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHN 465
            ...||.:|..:.:||.|.|.||..|...||.:.||:||.||||||||..|...::.:.:||.::
 Frog   418 IFCIHRNPTVWKDPEVFDPLRFSSENSSKRHSHAFVPFAAGPRNCIGQNFAMNELKVAVALTLN- 481

  Fly   466 FRFELHPK-TPVPMKYTINNLLLGSEGGIHLNITK 499
             |:||.|. :..|:|..  .|:|.|:.|||:.:.|
 Frog   482 -RYELSPDLSKAPLKSP--QLVLRSKNGIHVYLKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a19	NP_611001.2	CYP6-like	67..494	CDD:410679	120/475 (25%)
cyp4b1.3	XP_002931492.1	CYP4B-like	76..510	CDD:410771	120/472 (25%)