Protein Alignment Cyp6a23 and ERG5

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 528
• Identity: 111/528 - (21%)
• Similarity: 210/528 - (39%)
• Gaps: 111/528 - (21%)

  Fly     5 LTLIALLVSLLLF------------MARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFR 57
            |.:.|.|:.:||.            :|..:..:|           ||.|     |....:...|.
Yeast    46 LKIFATLICILLVWDQVAYQIKKGSIAGPKFKFW-----------PIIG-----PFLESLDPKFE 94

  Fly    58 DYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIE 122
            :|..|:...  |.:....|.....:.:..:|.:::|  ..:.|....:....:..........::
Yeast    95 EYKAKWASG--PLSCVSIFHKFVVIASTRDLARKIL--QSSKFVKPCVVDVAVKILRPCNWVFLD 155

  Fly   123 GQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEE-MEK-IFSAKTTTGEGQVL--EIVDLVARYTA 183
            |:.....|..|...||...:....|.:.::.:: |:| :..:|....|.||.  |:.:::
Yeast   156 GKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREIL----- 215

  Fly   184 DVIGNCAFGLN--CNSLQNPNAEFVTIGK-RAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDV 245
                 ||..||  |.:       ::|..: |.|.:..|.......:..||         :.:...
Yeast   216 -----CALSLNSFCGN-------YITEDQVRKIADDYYLVTAALELVNFP---------IIIPYT 259

  Fly   246 EDFYTSIVRNTIDYRLRTNE------KRH--------DFMDSLIEMYEKEQAGNTEDGLSF---- 292
            :.:|.   :.|.|..::..|      |.|        ..||:..::....:..|.:|...:
Yeast   260 KTWYG---KKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREF 321

  Fly   293 -NEILAQAFIFFVAGFETSSTTMGFALYELALDQ-DIQDQLRAEINNVLSKHNN----EFTYEGI 351
             |:.:::|...|:...:.:|:::...|:::..|: |:..::|.|   .|:..||    |...:.|
Yeast   322 TNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREE---QLAVRNNDMSTELNLDLI 383

  Fly   352 KEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVV---IPALGIHYDPEIYPE 413
            ::|||...|:.||||..|.:..:..:.:.:| |..|.|...||..::   .|||   :|||:|..
Yeast   384 EKMKYTNMVIKETLRYRPPVLMVPYVVKKNF-PVSPNYTAPKGAMLIPTLYPAL---HDPEVYEN 444

  Fly   414 PEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTE---TQ 475
            |::|.|||:.:.:.|:.....||.||.||..|:|      |..|.:.:.....||::.|:   |.
Yeast   445 PDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLG------QTYVMITFAALLGKFALYTDFHHTV 503

  Fly   476 IPMKFVVK 483
            .|:...:|
Yeast   504 TPLSEKIK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	104/485 (21%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	97/455 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940