Protein Alignment Cyp6a23 and DIT2

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 527
• Identity: 119/527 - (22%)
• Similarity: 194/527 - (36%)
• Gaps: 130/527 - (24%)

  Fly     3 LLLTL----IALLVSLLLFMARRRHGYWQRRGIPHDVPH-PIYGNMKDWPKKRHIAMIF------ 56
            |.|||    .|::|..|.|              |.::|. |.|        ...:.:||
Yeast    11 LFLTLSYVAFAIIVPPLNF--------------PKNIPTIPFY--------VVFLPVIFPIDQTE 53

  Fly    57 -RDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSA---- 116
             .|.|.:.....|....|:|....:.:::..|.:.:: .||.:.|...|   |:...|.||
Yeast    54 LYDLYIRESMEKYGAVKFFFGSRWNILVSRSEYLAQI-FKDEDTFAKSG---NQKKIPYSALAAY 114

  Fly   117 ---TLFSIEGQKWRHLRHKLT---------PTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEG 169
               .:.|..|..||:.|:.:|         |.|.:.|:  :..:|             |....||
Yeast   115 TGDNVISAYGAVWRNYRNAVTNGLQHFDDAPIFKNAKI--LCTLI-------------KNRLLEG 164

  Fly   170 QV-LEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEF----VTIGKRAIIERRYGGLLDFLIFGF 229
            |. :.:..|..|...|.|...|.|.:..:|.:....|    :.|.|:  |...:     ||.|.|
Yeast   165 QTSIPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIRIKKQ--IFHPF-----FLTFPF 222

  Fly   230 ----PKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQ-------- 282
                |..||:...|    ||..|...:|:..              .|.|:..|:.||
Yeast   223 LDVLPIPSRKKAFK----DVVSFRELLVKRV--------------QDELVNNYKFEQTTFAASDL 269

  Fly   283 --AGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELA-LDQDIQDQLRAEINNVLSKHNN 344
              |.|.|. :.:.::.....|..|||.|........:||.|| ...:.|::||.|:|.:...
Yeast   270 IRAHNNEI-IDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDP--- 330

  Fly   345 EFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPE 409
                :|:.::..|...:.|.:|.||.|:.:.....|.......:..|.||..|.....|..:||:
Yeast   331 ----KGLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPK 391

  Fly   410 IY-PEPEKFKPERFTDEAIAARPS-------CTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGY 466
            .: ...:.|||||:..:....|.:       |....|..|.|.|:|.:..|.:..:.||.:::.:
Yeast   392 TWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQF 456

  Fly   467 KFSVSTE 473
            ::|:..|
Yeast   457 RWSLDPE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	103/450 (23%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	103/451 (23%)