DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a23 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	118/495 - (23%)
Similarity:	211/495 - (42%)	Gaps:	86/495 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSVYPFAGFYFFFTRSAVIT-DLELVKRVLIK 95
            ||:..|.:..:..:|.:                  ||.....|:|.::..|.| |..|::..|..
plant    71 PHEFVHRVAPHYHEWSR------------------VYGKTFLYWFGSKPVVATSDPRLIREALTT 117

  Fly    96 DFNHFENRGIFYNEIDDPLSATLFS-----IEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEE 155
            . ..|:..|      .:|||..|::     :.|.:|...|......||..|:|...|.:|.....
plant   118 G-GSFDRIG------HNPLSKLLYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQMVTSTMM 175

  Fly   156 MEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIER--RY 218
            :.:.:......||...||:...:...:|:::...|||   ||::.....|      .:.||  |.
plant   176 LMEKWEDMRNGGEEIELEVHKEMHNLSAEMLSRTAFG---NSVEEGKGIF------ELQERMMRL 231

  Fly   219 GGLLDFLIF-----GFP--------KLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDF 270
            ..|:.:.::     .||        ::.:::|:.: ::.:|:..|::            ||....
plant   232 FYLVRWSVYIPGFRFFPSKTNREIWRIEKQIRVSI-LKLIENNKTAV------------EKSGTL 283

  Fly   271 MDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEI 335
            :.:.:..|..:  ...|:.|...|:..:...|:.|..||::..|.|.|..||::|:.|:..|.|:
plant   284 LQAFMSPYTNQ--NGQEEKLGIEEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEWQNIAREEV 346

  Fly   336 NNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMT--QTDFSPEDPKYFIAKGTTVV 398
            ..||.:.... |.:.::::|.|..::.||||.||....|.|.|  :......|    |..||.:.
plant   347 ICVLGQTGLP-TLDILQDLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGDLD----IPAGTQLY 406

  Fly   399 IPALGIHYDPEIY-PEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYL 462
            :..:.:|:|.|.: .:.|:|.|.||.|   ..:.|...:|||.|||.|:|....:.:|...||.:
plant   407 LSVVAMHHDKETWGDDAEEFNPRRFED---PKKQSALLVPFGLGPRTCVGQNLAVNEAKTVLATI 468

  Fly   463 IRGYKFSVS-TETQIPMKFVVKSILLSAENGIHLKVEKLS 501
            ::.|.|.:| :....|:.||.    |..:||.||...::|
plant   469 LKYYSFRLSPSYAHAPVLFVT----LQPQNGAHLLFTRIS 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	113/483 (23%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	113/484 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900