DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a23 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	134/519 - (25%)
Similarity:	230/519 - (44%)	Gaps:	72/519 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLLLTLIALLVSLLLFMARRRHGYW-----------------QRRGIPHDVPHPIYGNMKDWPK 48
            |.|:.|:..|.:.||||:..:   .|                 :::||.......:|||:.:..|
plant     1 MELISTINLLTIVLLLFVVSK---IWKACWILLLRPLMLSKRFKKQGISGPKYKILYGNLSEIKK 62

  Fly    49 KRHIA----------MIFRDYYTKYKRSVYPFAGFYFFFT---RSAVITDLELVKRVLIKDFNHF 100
            .:..|          .||...:.:|.:.:..:...:.|:|   .:..|::.||.|:||...|
plant    63 MKKEADLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKF--- 124

  Fly   101 ENRGIFYNEIDDPLSATLFS-----IEGQKWRHLRHKLTPTFTSGKMKNMF-PI---IVKVGEEM 156
               |.....:..|....||.     |:|..|...|..|.|.|:..::|.|. |:   .:::.||.
plant   125 ---GFTIIPVKRPEVFILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEW 186

  Fly   157 EKIFSAKTTTGEGQV-LEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGK-RAIIERRY- 218
            .|    :...||..: :||.....:.|||:|...|||       :..||.:.:.: :..:|:.|
plant   187 RK----QRRNGEVLIKIEISKEFHKLTADIIATTAFG-------SSYAEGIELCRSQTELEKYYI 240

  Fly   219 GGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLI-EMYEKEQ 282
            ..|.:..|.|...|.....|||  .::.....:.::..||.||::..|.:.:.|.|: .|....:
plant   241 SSLTNVFIPGTQYLPTPTNLKL--WELHKKVKNSIKRIIDSRLKSKCKTYGYGDDLLGVMLTAAK 303

  Fly   283 AGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFT 347
            :...|..:..:||:.:...|:.||..|:|..:.:....|:|.|..|::||.|:.|...|.....|
plant   304 SNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEVFNECGKDKIPDT 368

  Fly   348 YEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYP 412
             :...::|.:..|:||:||.|..:..::|....|......:  |.|||:::||.|.:|.|..|:.
plant   369 -DTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGHLE--IPKGTSIIIPLLKMHRDKAIWG 430

  Fly   413 E-PEKFKPERFTDEAIAA--RPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTE 473
            | .|:|.|.||.:....|  .|:.. |||..|||.||...|.:::|...|..:::.::.|:|.|
plant   431 EDAEQFNPLRFENGISQATIHPNAL-LPFSIGPRACIAKNFAMVEAKTVLTMILQQFQLSLSPE 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	123/467 (26%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	131/511 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810