DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a23 and CYP72A13

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188084.1	Gene:	CYP72A13 / 820694	AraportID:	AT3G14660	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	138/517 - (26%)
Similarity:	236/517 - (45%)	Gaps:	84/517 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLLLTLIALLVSLLLFMARRR--------HGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMI--- 55
            |:.:::..::||..::...:|        ..|.:|:|:......|:.|::     ||:.:|:
plant     7 SVTVSVAVVVVSWWVWRTLQRVWLKPKMLESYLRRQGLAGTPYTPLVGDL-----KRNFSMLAEA 66

  Fly    56 ------FRDYYTKYKRSV-YPF-------AGFYFFFTRSAVIT--DLELVKRVLIKDFNHFENRG 104
                  ..|..|  .|.| ||.       ..|:.:|.....||  |.|.:|.|..|.:: |:...
plant    67 RSKPINLTDDIT--PRIVPYPLQMLKTHGRTFFTWFGPIPTITIMDPEQIKEVFNKVYD-FQKAH 128

  Fly   105 IFYNEIDDPL----SATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVK-----VGEEMEKIF 160
            .|      ||    :|.|.|.:|.||...|..:.|.|...|:|||.|...:     || |.:|:.
plant   129 TF------PLGRLIAAGLVSYDGDKWTKHRRIINPAFHLEKIKNMVPAFHQSCSEIVG-EWDKLV 186

  Fly   161 SAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCN------SLQNPNAEFVTIG-KRAIIE-RR 217
            :.|.::.|   ::|...:...|||||...|||.:..      .||...|:.:... ::|||. .|
plant   187 TDKQSSCE---VDIWPWLVSMTADVISRTAFGSSYKEGQRIFELQAELAQLIIQAFRKAIIPGYR 248

  Fly   218 YGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQ 282
            |          ||....| |:|...::::    .|:|..::.|||..|......|.|:.:..:..
plant   249 Y----------FPTKGNR-RMKAAAREIK----FILRGIVNKRLRAREAGEAPSDDLLGILLESN 298

  Fly   283 AGNTE-DGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEF 346
            .|.|: :|:|..|::.:..:|:.||.||::..:.:.:..|:..||.|.:.|.|:..|..  :.|.
plant   299 LGQTKGNGMSTEELMEECKLFYFAGQETTTVLLVWTMVLLSQHQDWQARAREEVKQVFG--DKEP 361

  Fly   347 TYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY 411
            ..||:.::|.:..::.|.||.||.:..|||....:....|  ..:..|..:.:|.|.|..|.|::
plant   362 DAEGLNQLKVMTMILYEVLRLYPPVVQLTRAIHKEMQLGD--LTLPGGVQISLPILLIQRDRELW 424

  Fly   412 -PEPEKFKPERFTDE-AIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVS 471
             .:..:|||:||.|. :.|.:...::.||..|||.|||..|.|::|.:.:..::|.:.|.:|
plant   425 GNDAGEFKPDRFKDGLSKATKNQVSFFPFAWGPRICIGQNFALLEAKMAMTLILRKFSFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	131/475 (28%)
CYP72A13	NP_188084.1	p450	24..512	CDD:299894	135/500 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810