DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a23 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	489	Identity:	127/489 - (25%)
Similarity:	217/489 - (44%)	Gaps:	66/489 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FMARRRHGYWQRRGIPHDVPHPIYGNMKD----WPKKRHIAMIFRDYYT----KYKRSVYPFAGF 73
            |..:....|.:|:|:......|:.|::|.    ..:.|...:...|..|    .|...:....|.
plant    30 FKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEARSKPINLTDDITPRIVPYPLQMLKTHGR 94

  Fly    74 YFFFTRSAV----ITDLELVKRVLIKDFNHFENRGIFYNEIDDPLS---AT-LFSIEGQKWRHLR 130
            .||....|:    |.|.|.:..||.|.:: |:....|      ||.   || :.|.:|.||...|
plant    95 TFFTWFGAIPTITIMDPEQITEVLNKVYD-FQKAHTF------PLGRLIATGVLSYDGDKWAKHR 152

  Fly   131 HKLTPTFTSGKMKNMFPIIVKVGEEM----EKIFSAKTTTGEGQVLEIVDL---VARYTADVIGN 188
            ..:.|.|...|:|||.|...:...|:    :|:.|.|.::.|      ||:   :...|||||..
plant   153 RIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESSCE------VDVWPGLVSMTADVISR 211

  Fly   189 CAFGLNC------NSLQNPNAEFV--TIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDV 245
            .|||.:|      ..||...|:.:  |:.|..|....|          .|....| |:|...:::
plant   212 TAFGSSCVEGQRIFELQAELAQLIIQTVRKAFIPGYSY----------LPTKGNR-RMKAKAREI 265

  Fly   246 EDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTE-DGLSFNEILAQAFIFFVAGFET 309
            :    .|:|..::.|||..|......|.|:.:..:...|.|: :|:|..:::.:..:|:..|.||
plant   266 Q----VILRGIVNKRLRAREAGEAPNDDLLGILLESNLGQTKGNGMSTEDLMEECKLFYFVGQET 326

  Fly   310 SSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHL 374
            :|..:.:.:..|:..||.|.:.|.|:..|..  :.|...||:.::|.:..::.|.||.||.:..|
plant   327 TSVLLVWTMVLLSQHQDWQARAREEVKQVFG--DKEPDAEGLNQLKVMTMILYEVLRLYPPIPQL 389

  Fly   375 TRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERFTDE-AIAARPSCTWLP 437
            :|....:....|  ..:..|..:.:|.|.:..|.|:: .:..:|||:||.|. :.|.:...::.|
plant   390 SRAIHKEMELGD--LTLPGGVLINLPILLVQRDTELWGNDAGEFKPDRFKDGLSKATKNQASFFP 452

  Fly   438 FGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVS 471
            |..|.|.|||..|.|::|.:.:|.:::.:.|.:|
plant   453 FAWGSRICIGQNFALLEAKMAMALILQRFSFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	123/470 (26%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	127/489 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810