DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a23 and CYP72A10

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188082.2	Gene:	CYP72A10 / 820692	AraportID:	AT3G14640	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	128/522 - (24%)
Similarity:	230/522 - (44%)	Gaps:	75/522 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRS--------VYPFA-- 71
            |..:....|.:|:|:......|:.|::     ||::.|:........|.:        .:||.
plant    52 FKPKMLESYLRRQGLAGTPYTPLIGDL-----KRNVNMLTEATSKPIKLTEDITPRVLPHPFQML 111

  Fly    72 ---GFYFFF----TRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHL 129
               |..||.    ..:..|.|.||:|.|..|.:::.:.:......:   ::..:.:.:|.||...
plant   112 KTHGRTFFTWLGPKPTITIMDPELIKEVFNKVYDYPKAQTFLLGRL---IATGIINYDGDKWAKH 173

  Fly   130 RHKLTPTFTSGKMKNMFPIIVK-----VGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNC 189
            |..:.|.|...|:|||.|...:     |||..:.:....:::.|   :::...:...|.|||...
plant   174 RRIINPAFHIEKIKNMVPAFHQSCSDVVGEWSKLVSDKGSSSCE---VDVWPWLVSMTGDVISRT 235

  Fly   190 AFGLNCNSLQ---NPNAEFVTIGKRA-----IIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVE 246
            |||.:....|   ...||.|.:..:|     |...||          .|..|.| |:|...::::
plant   236 AFGSSYKEGQRIFELQAELVHLILQAFWKVYIPGYRY----------LPTKSNR-RMKAAAREIQ 289

  Fly   247 DFYTSIVRNTIDYRLRTNE-----KRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAG 306
                .|::..::.|||..|     ...|.:..|:|....:..||   |:|..:::.:..:|:.||
plant   290 ----VILKGIVNKRLRAREAGKAAPNDDLLGILLESNLGQAKGN---GMSTEDVMEECKLFYFAG 347

  Fly   307 FETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVL 371
            .||:|..:.:|:..|:..||.|.:.|.|:..|..  :.|...|.:.::|.:..::.|.||.||.:
plant   348 QETTSVLLVWAMVLLSHHQDWQARAREEVKQVFG--DKEPDTECLSQLKVMTMILYEVLRLYPPV 410

  Fly   372 AHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERFTDE-AIAARPSCT 434
            .||||....:....|  ..:..|..:.:|.:.:..||.:: .:..:||||||.|. :.|.:...:
plant   411 THLTRAIDKEMKLGD--LTLPAGVHISLPIMLVQRDPMLWGTDAAEFKPERFKDGLSKATKSQVS 473

  Fly   435 WLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVS-TETQIPMKFVVKSILLSAENGIHLKVE 498
            :.||..|||.|||..|.:::|.:.:|.:::.:.|.:| :....|...|.    :..:.|.||.:.
plant   474 FFPFAWGPRICIGQNFAMLEAKMAMALILQTFTFELSPSYVHAPQTVVT----IHPQFGAHLILR 534

  Fly   499 KL 500
            ||
plant   535 KL 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	120/496 (24%)
CYP72A10	NP_188082.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810