DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a23 and CYP72A8

DIOPT Version :9

Sequence 1:	NP_611000.2	Gene:	Cyp6a23 / 36661	FlyBaseID:	FBgn0033978	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188080.1	Gene:	CYP72A8 / 820690	AraportID:	AT3G14620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	134/493 - (27%)
Similarity:	219/493 - (44%)	Gaps:	81/493 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RRRHGYWQRRGIPHDVPHPIYGNMK------DWPKKRHIAMIFRDYYT------------KYKRS 66
            ::...|.:|:|:.......:.|::|      :..|.|.|.:  .|.||            .:.::
plant    37 KKNEAYLKRQGLSGTPFTFLVGDIKREASMVEQEKSRPINL--TDDYTHRVMPLIQQTVKDHGKT 99

  Fly    67 VYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLS--ATLFS-----IEGQ 124
            .|.:.|    ...|.::|..|.:|.||        ||  .|:....|:.  ..||:     .||:
plant   100 SYMWMG----PIASVIVTKPEHIKDVL--------NR--VYDFPKPPVHPIVELFATGVALYEGE 150

  Fly   125 KWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEM----EKIFSAKTTTGEGQVLEIVDLVARYTADV 185
            ||...|..:.|:|...|:|.|.|...:...||    ||:.   |..|....:::...:...|:||
plant   151 KWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWEKLV---TEQGSSNEIDVWPYLGDLTSDV 212

  Fly   186 IGNCAFGLNCNSLQNPNAEFVTIGKR--AIIERRYGGLLDFLIFGFPKLSRRLRLK--LNVQDVE 246
            |...|||.:...           |||  .:.|.:...:|..|...|....|.|..|  |.::.:.
plant   213 ISRTAFGSSYEE-----------GKRIFELQEEQGRRVLKALELAFIPGMRFLPTKNNLRMRQIN 266

  Fly   247 DFYTSIVRNTIDYRLR---TNE-KRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGF 307
            ....|.:|..|..|.|   |.| .::|.:..|:|      :.:.:.|:|..:::.:..:|..||.
plant   267 KEVKSRLREIIMKRQRGMDTGEAPKNDLLGILLE------SNSGDHGMSIEDVVEECRLFHFAGQ 325

  Fly   308 ETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYP--V 370
            ||::..:.:.:..|:..|..|||.|.||..|:.| ||:..::.:..:|.:..::.|.||.||  :
plant   326 ETTAVLLVWTMIMLSHHQKWQDQAREEILKVIGK-NNKPNFDALSRLKTMSMILNEVLRLYPPGI 389

  Fly   371 LAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEP-EKFKPERFTDE-AIAARPSC 433
            |...|...:|... ||  ..:..|..||||.|.:|.|||::.|. .:|.||||.|. :.|.:...
plant   390 LLGRTVEKETKLG-ED--MTLPGGAQVVIPVLMVHRDPELWGEDVHEFNPERFADGISKATKNQV 451

  Fly   434 TWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVS 471
            ::||||.|||.|.|..|.||:|.:.|..:::.:.|.:|
plant   452 SFLPFGWGPRFCPGQNFALMEAKMALVLILQRFSFELS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	131/477 (27%)
CYP72A8	NP_188080.1	p450	26..515	CDD:299894	134/493 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810