Protein Alignment Cyp6a23 and cyp3a65

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.2
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 515
• Identity: 169/515 - (32%)
• Similarity: 263/515 - (51%)
• Gaps: 35/515 - (6%)

  Fly     6 TLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSVYPF 70
            ||:|.||:||:......|.|:::.|||.....|.:|.|..:....|:  ...|.:.||.|    .
Zfish     9 TLLAFLVALLVIYGSWPHRYFKKLGIPGPKTIPFFGTMLRYKDGFHV--FDMDCFEKYGR----I 67

  Fly    71 AGFYFFFTRSAVITDLELVKRVLIKD-FNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKLT 134
            .|.|........|.|..::|.||||: ::.|.||..|  .::..|...:...|...||.:|..|:
Zfish    68 WGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNF--RLNGALYDAVSIAEDDDWRRIRSVLS 130

  Fly   135 PTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQ 199
            |:||||::|.||.|:.|....:  :.|...|...|:..:|.:....|:.||:.:.||.::.:||.
Zfish   131 PSFTSGRLKEMFGIMKKHSHIL--VDSMGKTAKRGESADIKEFFGAYSMDVVTSTAFSVDIDSLN 193

  Fly   200 NPNAEFVTIGKRAIIERRYGGL--LDFLIFGFPKLS---RRLRLKLNVQDVEDFYTSIV------ 253
            ||...|||..|:.:   ::..|  |..||..||.::   .::...|....|.||:.:.:
Zfish   194 NPKDPFVTNIKKML---KFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSD 255

  Fly   254 RNTIDYRLRTNEKRHDFM----DSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTM 314
            |:|........:||.||:    ||...:..|....:||.|||.:|||:|:.||..||:||||:|:
Zfish   256 RDTKTVAKDNTKKRVDFLQLMVDSQTGVKHKSDGEHTEKGLSDHEILSQSMIFIFAGYETSSSTL 320

  Fly   315 GFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQ 379
            .|..|.||.:.:...:|:.||:... .:.....||.:..|.||:..:.|:||.|||.|.|.|:.:
Zfish   321 SFLFYNLATNPETMKKLQEEIDETF-PNQAPVDYETLMSMDYLDAALSESLRLYPVAARLERVCK 384

  Fly   380 TDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRN 444
            .  :.|.....|.|...|::|...:|.||:.:.|||.|||||||.....:.....::|||.||||
Zfish   385 K--TVEINGLLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRN 447

  Fly   445 CIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVE--KLSK 502
            |||:||..:...:.:..:::.:..||..|||:|::..... |||.::.|.||::  |||:
Zfish   448 CIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNG-LLSPKDPIKLKLQPRKLSQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	143/441 (32%)
cyp3a65	NP_001032515.2	cytochrome_P450	63..498	CDD:477761	147/449 (33%)