Protein Alignment Cyp6a23 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 130/545 - (23%)
• Similarity: 237/545 - (43%)
• Gaps: 98/545 - (17%)

  Fly     1 MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVP--HPIYGNMKDWPKKRHIAMIFRD----- 58
            ::||..::.||.:..|:...||   :....:|...|  |.:||         |:....||
 Frog    25 VALLCVVLLLLKAYALYSRGRR---FAAALVPFPGPPAHWLYG---------HVNQFRRDGKDLD 77

  Fly    59 ----YYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENR-GIFYNEIDDPLSATL 118
                :..||..:...:.|.:|   .:.:|||.:..|.|    |...:.: ...||.:...:...|
 Frog    78 RLMVWVNKYPNAFPLWIGKFF---GTLIITDPDYAKVV----FGRSDPKTSTGYNFLVPWIGKGL 135

  Fly   119 FSIEGQKWRHLRHKLTPTFTSGKMKNMFPII---VKVGEEMEKIFSAKTTTGEGQVLEIVDLVAR 180
            ..:.|..|...|..:||.|....:|....:|   .|:..:...::|.|     .:.:|:...|:.
 Frog   136 LILSGNTWFQHRRLITPGFHYDVLKPYVSLISDSTKIMLDELDVYSNK-----DESVELFQHVSL 195

  Fly   181 YTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERR------------YGGLLDFLI---FGFP 230
            .|.|.|..|||..:.|...:.:.:::    :|:.:..            :..|:.||.   |.|.
 Frog   196 MTLDSIMKCAFSYHSNCQTDKDNDYI----QAVYDLSWLTQQRIRTFPYHSNLIYFLSPHGFRFR 256

  Fly   231 K------------LSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRH-DFMDSLIEMYEKEQ 282
            |            :.:|.:|..:.:::|               :..:||| ||:|.|  :..|::
 Frog   257 KACRIVHLHTDKVIGQRKKLLESKEELE---------------KVQKKRHLDFLDIL--LCSKDE 304

  Fly   283 AGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFT 347
            .|   .|||..::.|:...|...|.:|:|:.:.:.||.:|...:.|.:.|.||:..|.:... ..
 Frog   305 NG---QGLSHEDLRAEVDTFMFEGHDTTSSGISWILYCMATHPEHQQKCREEISEALGERQT-ME 365

  Fly   348 YEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYP 412
            ::.:..|.|....:.|:||.||.:..::|......:..|.:...| |..|.:....||.:|.::.
 Frog   366 WDDLNRMPYTTMCIKESLRLYPPVPSVSRELAKPITFHDGRSLPA-GMLVSLQIYAIHRNPNVWK 429

  Fly   413 EPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTE-TQI 476
            :||.|.|.||:.|..:.|.|..::||..|||||||..|.:.:..|.:|..::  :|.:|.: ::.
 Frog   430 DPEIFDPLRFSPENSSKRHSHAFVPFAAGPRNCIGQNFAMNEMKVAVALTLK--RFELSPDLSKP 492

  Fly   477 PMKFVVKSILLSAENGIHLKVEKLS 501
            |:|  ...::|.::||||:.::|.|
 Frog   493 PLK--QPQLVLRSKNGIHVYLKKAS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	109/458 (24%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	113/475 (24%)