Protein Alignment Cyp6a23 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 484
• Identity: 124/484 - (25%)
• Similarity: 208/484 - (42%)
• Gaps: 87/484 - (17%)

  Fly    55 IFRDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLI-----KD-------FNHFENRGIFY 107
            :|..:..|| ..||.....::.   :.|:...|..|.:|:     ||       ||.|..|.:.|
Zfish    11 LFLQWAEKY-GPVYRINSLHYI---AIVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGY 71

  Fly   108 NEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGE----EMEKIFSAKTTTGE 168
            ..|.        :::...|...|..:.|.|:|..::::.....::.|    ::|::.:.||..
Zfish    72 GLIT--------AVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPA-- 126

  Fly   169 GQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGG----LLDFLIFGF 229
              |:.  |||...|.|||...|||::.|.|...::.|     :..:|....|    |.|.....|
Zfish   127 --VMH--DLVNCVTLDVICKVAFGVDLNFLTQKDSPF-----QNAVELCLNGMTVDLRDPFFRLF 182

  Fly   230 PKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEK---------------RHDFMDSLIEMYE 279
            ||     ..||..|         :|:..:...:|.||               ..|.:..:::..|
Zfish   183 PK-----NWKLIKQ---------IRDAAELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAE 233

  Fly   280 KEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNN 344
            :|...||:|   ..::|.....||:||.||::..:.||:..|..:.:|..:.:||::.||.. ..
Zfish   234 EENVNNTDD---LEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGT-KR 294

  Fly   345 EFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPE 409
            |.:.|.:.:..||.||:.||||.||......|....|...:..|  |..|.:|:..:.......:
Zfish   295 EISNEDLGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMIIDGIK--IPGGCSVMFSSYVSQRLEK 357

  Fly   410 IYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTET 474
            .:.:|.||.||||  :..|.:|...:.||..|||.|:|..|..|:|.|.||.|::.::||:
Zfish   358 FFKDPLKFDPERF--DVNAPKPYYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFEFSL---- 416

  Fly   475 QIP-MKFVVKSI-LLSAENGIHLKVEKLS 501
             :| ..|.:|.. .|..::|:...:::.|
Zfish   417 -VPGQSFDIKDTGTLRPKSGVICNIKQCS 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	119/462 (26%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	123/476 (26%)