Protein Alignment Cyp6a23 and Cyp6d2

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 164/524 - (31%)
• Similarity: 274/524 - (52%)
• Gaps: 59/524 - (11%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQRRGI---PHDVPHPIYGN-MKDWPKKRHIAMIFRDYYTK 62
            ::|||:  |:..||....:|.:.:|||.|:   |..:|..:... ||   ::|.:.|...|.|.:
  Fly     3 TILLTI--LIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMK---QERSLGMALADIYAR 62

  Fly    63 YKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWR 127
            ::..:   .|.|....||.:|.|.:|.::::..||..|.:||::.:|..|||||.||::.|..||
  Fly    63 HEGKI---VGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFNLRGASWR 124

  Fly   128 HLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFG 192
            :||.||||:|:|||:|.||..|..||:::  :...:....:...:||.|::..|..|:||:..||
  Fly   125 NLRQKLTPSFSSGKIKGMFGTIDDVGDKL--VQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFG 187

  Fly   193 LNCNSLQNPNAEFVTIGKRAIIER----RYGGLLDFLIFGFPKLSRRL----RLKLNVQDVEDFY 249
            |..:|.:||..||..|......:.    :...:..|:.....||..||    |:..:::|
  Fly   188 LEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGYESRILTSLRD----- 247

  Fly   250 TSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTED-------------GLSFNEILAQAFI 301
              :::.||::|...|..|.|.:..||.:....:.|..:|             .:|..:|.||||:
  Fly   248 --MMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAFL 310

  Fly   302 FFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHN----NEFTYEGIKEMKYLEQVVM 362
            |:|||.|:::....|.||||::..::..:.:.|::.||.|||    :.||||.::::|:|:..:|
  Fly   311 FYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIM 375

  Fly   363 ETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFT---- 423
            ||:||||.|..|.|....|:......:.|||||.::|...|:..||..:|.|..:.|.||.
  Fly   376 ETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNNM 440

  Fly   424 --DEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSIL 486
              |:|       .::|||||||:||.||.|.:.:.|.:|.::..:....|...::..:|....:|
  Fly   441 NYDQA-------AYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVL 498

  Fly   487 LSAE 490
            ::.|
  Fly   499 VTKE 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	152/487 (31%)
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	145/457 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461164
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900