Protein Alignment Cyp6a23 and Cyp6a8

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 249/501 - (49%)
• Similarity: 354/501 - (70%)
• Gaps: 7/501 - (1%)

  Fly     3 LLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSV 67
            :|..:...|:::|.:...|:..|::|||||...||.|.|||::..|.::|..||:|:|.|::.|.
  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESK 70

  Fly    68 YPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHK 132
            .||.||:||.:.:|.:.||||.|::|||||::|.|:||||||.|||:||.||:::|.:||.||:|
  Fly    71 APFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNK 135

  Fly   133 LTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNS 197
            |:.||||||||.|:|.:|.|..|...:...|..  :..||||.|||||:|.||||.||||:.|||
  Fly   136 LSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVP--KNSVLEIRDLVARFTVDVIGTCAFGIQCNS 198

  Fly   198 LQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLR 262
            |::..|||:..|||:::::|:|.||:..:..:|||:|:|.:......:::||:.||..|:..|.:
  Fly   199 LRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREK 263

  Fly   263 TNEKRHDFMDSLIEMYEKEQA----GNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELAL 323
            .:.||:||||.|||:..:::.    |:...||:..|:|||||:||:|||||||:||||||||||.
  Fly   264 EHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAK 328

  Fly   324 DQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDF-SPEDP 387
            :.||||::|||:..|:.:|:..||||..|::|||.||:.||||.|.::.:|.||....: .|..|
  Fly   329 NPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHP 393

  Fly   388 KYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGL 452
            .:.|..|.:|:||:..||:||.|||||.:|:||||:.|..|.|||..|||||:|||||||||||.
  Fly   394 NFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQ 458

  Fly   453 MQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVE 498
            |||.:|||.|||.:|||..::|..|:.:..||.:|..::||:||||
  Fly   459 MQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	235/463 (51%)
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	236/465 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471813
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800