Protein Alignment Cyp6a23 and Cyp4e2

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 133/563 - (23%)
• Similarity: 243/563 - (43%)
• Gaps: 111/563 - (19%)

  Fly     3 LLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPK--KRHIAMIFRDYYTKYKR 65
            :.|.|..|||:.|.....||.....:...|..:  |:.||.....|  ...:..:| .::.:|.:
  Fly     7 IFLALPLLLVAYLELSTFRRRRVLNKFNGPRGL--PLMGNAHQMGKNPSEILDTVF-SWWHQYGK 68

  Fly    66 SVYPF-AGFY------------FFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDP-LSA 116
            ..:.| .|.|            |..:...:||..::.                   ::..| |..
  Fly    69 DNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIY-------------------QLTHPWLGL 114

  Fly   117 TLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEK-IFSAKTTTGEGQVLEIVDLVAR 180
            .|.:..|.||...|..:||.|....:::...:   :.|...| |...||......:.:..:....
  Fly   115 GLLTSTGSKWHKHRKMITPAFHFNILQDFHEV---MNENSTKFIKHLKTVAAGDNIFDFQEQAHY 176

  Fly   181 YTADVIGNCAFGLNCNSLQNPNAEFV--------TIGKRAIIERRYGGLLDFLIFGFPKLSRRLR 237
            .|.|||.:.|.|::.|:::|.::..|        .|..||....:...||..|...:|..||.|:
  Fly   177 LTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLK 241

  Fly   238 LKLNVQDVEDFYTSIVRNTIDYR----LRTN------EKRHDFMDSLIEMYEKEQAGNTEDG--L 290
                  .::||...|:...|:..    :.||      .|:..|:|:|:        .:|.||  |
  Fly   242 ------TLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLL--------SSTIDGRPL 292

  Fly   291 SFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVL--SKHNNEFTYEGIKE 353
            :..|:..:...|...|.:|:::.:.||:|.|:..||.|.:|..|...|:  |:...:.|::.|.:
  Fly   293 NSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQ 357

  Fly   354 MKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFK 418
            ||||:..:.|..|.||.:..:.|.|:.|:..:..  .:.||||:.:..:.:.|:.:::.:|.||:
  Fly   358 MKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFR 420

  Fly   419 PERFTDEAIAARPS-CTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKF------------SV 470
            ||||..|    :|. ..::||..|||||||.:|.|::....::.:||.::.            .:
  Fly   421 PERFELE----KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI 481

  Fly   471 STETQIP-----------MKF--VVKSIL-LSAENGIHLKVEK 499
            ||...:|           .|:  ::.::| |.:|||:::::::
  Fly   482 STTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	118/489 (24%)
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	118/493 (24%)