Protein Alignment Cyp6a23 and Cyp6u1

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 170/506 - (33%)
• Similarity: 263/506 - (51%)
• Gaps: 33/506 - (6%)

  Fly     4 LLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPK-KRHIAMIFRDYYTKYKRSV 67
            |||.:..| |::..:.:...|||:||||.|:.|..::||:|.... |||.....:|.||.||...
  Fly     8 LLTALGAL-SVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYTAYKGRA 71

  Fly    68 YPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHK 132
             ||.|||.......:..||:||.:::..|..||.:||::.|...:|||..|..::|.|||.|..|
  Fly    72 -PFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKWRSLHAK 135

  Fly   133 LTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNS 197
            ....||...|:.:...:.::...:::....|:.    |.:.|.:||..|..||:.:.||||
  Fly   136 SAEVFTPANMQKLLVRLSQISSRIQRDLGEKSL----QTINISELVGAYNTDVMASMAFGL---- 192

  Fly   198 LQNPNAEFVTIGKRAIIERRYGGLLDF------LIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNT 256
            :...|.||      |...|.|..  ||      |...||.::|.|:.|...:....::..:..:.
  Fly   193 VGQDNVEF------AKWTRNYWA--DFRMWQAYLALEFPLIARLLQYKSYAEPATAYFQKVALSQ 249

  Fly   257 IDYRLRTNEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYEL 321
            :....|.:.:.   :.:.:::|     .|.|..|:..||..|||.|.:||....:.|:.|.||||
  Fly   250 LQLHRRRDRQP---LQTFLQLY-----SNAEKPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYEL 306

  Fly   322 ALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPED 386
            |...::||:.|.|||..|.:|..:.|.|.::|::|.:||:.||||.:.....|.|....:|....
  Fly   307 ARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPG 371

  Fly   387 PKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFG 451
            ..:.||||..|:||...||.||.||..|::|.||||.::|..:||:..:||||:|.|.||..||.
  Fly   372 SVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGCIAARFA 436

  Fly   452 LMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKLSK 502
            ..|..|||..|:|.::::.|.||.||:::..:.:||..::.|.|.||::.|
  Fly   437 EQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSVERVDK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	153/465 (33%)
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	152/461 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471842
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.900