Protein Alignment Cyp6a23 and Cyp4v3

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 136/538 - (25%)
• Similarity: 238/538 - (44%)
• Gaps: 86/538 - (15%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQR-RGIPHDV-PHPIYGN---MKDWPKK------------ 49
            ::||.::.:|||    .||:    ||: |.||... .:|:.|:   ||  |..
  Rat    28 TVLLNILQMLVS----YARK----WQQMRPIPSVARAYPLVGHALFMK--PNNTEFFQQIIQYTE 82

  Fly    50 --RHIAMIFRDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDD 112
              ||:.:|      |......|....|.......::|..:.:            ::...|..:..
  Rat    83 EFRHLPII------KLWIGPVPLVALYKAENVEVILTSSKQI------------DKSFMYKFLQP 129

  Fly   113 PLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQ-VLEIVD 176
            .|...|.:..|.|||..|..|||:|....:::...::    .|...|...|......| ......
  Rat   130 WLGLGLLTSTGSKWRARRKMLTPSFHFTILEDFLDVM----NEQANILVNKLEKHVNQEAFNCFF 190

  Fly   177 LVARYTADVIGNCAFGLNCNSLQNPNAEFV-TIGKRA-IIERR-----YGGLLDFLIFGFPKLSR 234
            .:.....|:|...|.|.|..:..|.::|:| |:.:.: :|.||     :...|.:|:|   |..|
  Rat   191 PITLCALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMF---KEGR 252

  Fly   235 RLRLKLNVQDVEDFYTSIVRNTIDYR-------------LRTNEKRHDFMDSLIEMYEKEQAGNT 286
              ..|..::.:..|..:::...::.|             |.:..||..|:|.|:.:.::|  ||.
  Rat   253 --DHKKGLKSLHTFTNNVIAERVNARKAEQDCIGAGRGPLPSKTKRKAFLDLLLSVTDEE--GNK 313

  Fly   287 EDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGI 351
               ||..:|..:...|...|.:|::..:.::||.|..:.::|.::..|:::|..:.:...|.|.:
  Rat   314 ---LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHRPVTLEDL 375

  Fly   352 KEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEK 416
            |::|||:.|:.||||.:|.:....|....|.  |...|.|:|||..||....:|.||..:|:||:
  Rat   376 KKLKYLDCVIKETLRVFPSVPLFARSLSEDC--EVAGYKISKGTEAVIIPYALHRDPRYFPDPEE 438

  Fly   417 FKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFV 481
            |:||||..|....|....::||..|||||||.:|.:|:....||.::|  :|.:.:..:.....:
  Rat   439 FQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILR--EFWIESNQKREELGL 501

  Fly   482 VKSILLSAENGIHLKVEK 499
            ...::|...|||.:|:::
  Rat   502 AGDLILRPNNGIWIKLKR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	123/496 (25%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	118/474 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820