Protein Alignment Cyp6a23 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 156/535 - (29%)
• Similarity: 256/535 - (47%)
• Gaps: 64/535 - (11%)

  Fly     5 LTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFR----DYYTKYKR 65
            :||..:|::||.:.:.......::.||.|..|.|..||:          |.||    :.:.:.:.
  Rat    18 VTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPFVGNL----------MFFRQGFWESHLELRE 72

  Fly    66 SVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENR---GIFYNEIDDPLSATLFSIEGQKWR 127
            ...|..|:|.......||:|.:::|.||:::|::|.||   |:....|.|    ::..:..::|.
  Rat    73 RYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIAD----SVLMLRDRRWE 133

  Fly   128 HLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFG 192
            .:|..|...|:..|:..|.|:|.:..|.:  :...|.:...|...:|......:|.:|:.:.|||
  Rat   134 EVRGALMSAFSPEKLNEMTPLISQACELL--LSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFG 196

  Fly   193 LNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPK----LSRRLRLKLNVQDVEDFYTSIV 253
            :..||...|...||...:|.........|| .||..||.    |:|.|..| |..::..|:.:::
  Rat   197 IEVNSQDAPEDPFVQHCQRVFAFSTPRPLL-ALILSFPSIMVPLARILPNK-NRDELNGFFNTLI 259

  Fly   254 RNTIDYRLR--TNEKRHDFMDSLIE-------------------MYEKEQAG---------NTED 288
            ||.|..|.:  ..|:|.||:..:::                   :...|..|         :|..
  Rat   260 RNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQRCHPTSTAK 324

  Fly   289 GLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKE 353
            .|:.:||..|||:|.:||.|.::.|:.|..|.||...:.|::|..|::..:.||... .|..::|
  Rat   325 PLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAP-EYCNLQE 388

  Fly   354 -MKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKF 417
             :.||:.||.||||.||.....||....|.  |.....|..|:.:.|....:|:|||.:|.||.|
  Rat   389 GLPYLDMVVAETLRMYPPAFRFTREAAQDC--EVLGQHIPAGSVLEIAVGALHHDPEHWPNPETF 451

  Fly   418 KPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVV 482
            .|||||.||...:...|:||||.|||:|:|:|.||:...:.|..::..::|....|||:|::...
  Rat   452 DPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVPLQLES 516

  Fly   483 KSILLSAENGIHLKV 497
            || .|..:||:::|:
  Rat   517 KS-ALCPKNGVYVKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	140/463 (30%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	140/464 (30%)