Protein Alignment Cyp6a23 and Cyp4a2

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_038965182.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 134/564 - (23%)
• Similarity: 233/564 - (41%)
• Gaps: 134/564 - (23%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQRRGI---PHDVPHPIYG-NMKD--------WPKKRHIAM 54
            :.||:|..:|...:.|..||:   |..:.:   |....|.::| |:||        |.:|
  Rat    22 AFLLSLFLVLFKAVQFYLRRQ---WLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEK----- 78

  Fly    55 IFRDYYTKYKRSVYPFAGFYFF--FTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDP---- 113
                         :|.|...:.  .|...::.|.:.||.||.:               .||
  Rat    79 -------------FPGACLQWLSGSTARVLLYDPDYVKVVLGR---------------SDPKPYQ 115

  Fly   114 -----LSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVK----VGEEMEKIFSAKTTTGEG 169
                 :...|..:.|:||...|..|||.|....:|....|:..    :.::.||:      ..:.
  Rat   116 SLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKL------DDQD 174

  Fly   170 QVLEIVDLVARYTADVIGNCAFG------LNCNSLQNPNA-----EFVTIGKRAIIERRYGGLLD 223
            ..|||...|:..|.|.:..|||.      |:.||.....|     ..:....|:..   ||..:.
  Rat   175 HPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAF---YGNSII 236

  Fly   224 FLIFGFPKLSRR------------------LRL--------KLNVQDVEDFYTSIVRNTIDYRLR 262
            :.:....:||||                  |.|        |..:|:.|:..            :
  Rat   237 YNMSSDGRLSRRACQIAHEHTGSVFLLPAFLSLSDGVIKTRKAQLQNEEELQ------------K 289

  Fly   263 TNEKRH-DFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQD 326
            ..:||| ||:|.|  ::.|.:.|.:   ||..::.|:...|...|.:|:::.:.:..|.||...:
  Rat   290 ARKKRHLDFLDIL--LFAKMEDGKS---LSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPE 349

  Fly   327 IQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFI 391
            .|::.|.|:.::|. .....|::.:.:|.|....:.|.||.|..:..::|...:..:..|.: .|
  Rat   350 HQERCREEVQSILG-DGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGR-SI 412

  Fly   392 AKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQAC 456
            .||..|.|...|:|::|..:|.|:.|.|.||:.:  :.|.|..:|||..|.|||||.:|.:.:..
  Rat   413 PKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPD--SPRHSHAYLPFSGGARNCIGKQFAMNELK 475

  Fly   457 VGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500
            |.:|..:..::. :...|:||:.  :..::|.::|||||:::||
  Rat   476 VAVALTLLRFEL-LPDPTRIPVP--MPRLVLKSKNGIHLRLKKL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	121/520 (23%)
Cyp4a2	XP_038965182.1	CYP4B-like	69..512	CDD:410771	117/508 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910