Protein Alignment Cyp6a23 and Cyp4a29

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001093653.1
• Gene: Cyp4a29 / 230639
• MGIID: 3717143
• Length: 509
• Species: Mus musculus
• Alignment Length: 548
• Identity: 126/548 - (22%)
• Similarity: 226/548 - (41%)
• Gaps: 111/548 - (20%)

  Fly     4 LLTLIALLVSLLLFMARRRH--GYWQRRGI---PHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKY 63
            ::.||.||  ||||.|.:.:  ..|..|.:   |....|.::|:...:.....:..|.| |..|:
Mouse    21 VIFLIGLL--LLLFKAAQHYLRRQWLLRALYQFPSPPSHWLFGHCLQFKVDEELRWILR-YLEKF 82

  Fly    64 KRS-VYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWR 127
            ..: ::...|.:.|..    :.|.:.:|.:|    ...:.:...|..:...|...||.:.|.:|.
Mouse    83 PGAFLHWIWGSHVFIK----VCDPDYMKVIL----GRADPKASLYRFLTPWLGHGLFFLNGDEWF 139

  Fly   128 HLRHKLTPTFTSGKMKNMFPII---VKVG-EEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGN 188
            ..|..|||.|....:|....|:   |:|. |:.|:|.....|      |||...::....|.|..
Mouse   140 QHRRLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDIT------LEIFHPISLMMLDTIMK 198

  Fly   189 CAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLN-VQDVEDFYTS- 251
            .||...                                 |..:|.|..:..|. |.|:.:..||
Mouse   199 YAFSYQ---------------------------------GSVQLDRSSQAYLQAVSDLNNLVTSR 230

  Fly   252 ----IVRNTIDYRLRTNEKR--------HDFMDSLIEMYEKEQAGN------------------- 285
                .:.|.|.|.|.::.:|        |:..|.::::.:.:...|
Mouse   231 MKNVFLHNDIIYNLTSHSRRTNSACQIAHEHTDRVVKLRKAQLQDNKSMKKLRGKRCLDFLDILL 295

  Fly   286 ---TEDGLSFNE--ILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNE 345
               .:||.|.::  :.|:.......|.:|.::.:.:..|.||...|.|.:.|.|:.::|. ..:.
Mouse   296 LSRMDDGSSLSDKALRAEVDSLMFGGHDTPASGISWVFYALATHPDHQQRCREEVQSLLG-DGSP 359

  Fly   346 FTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEI 410
            .|::.:.:|.|....:.|.||.||.:..:.|...|..:..|.: .:.||.||::....:|::|::
Mouse   360 ITWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPVTFPDGR-SLPKGITVLLHFYALHHNPKV 423

  Fly   411 YPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIG--LRFGLMQACVGLAYLIRGYKFSVSTE 473
            :|.||.|.|.||...::  :.|..:|||..|.|||||  |...:::..|.|..|    :|.:..:
Mouse   424 WPNPEVFDPSRFAMNSV--QHSHAFLPFSGGSRNCIGKHLAMNVLKVAVALTLL----RFELLPD 482

  Fly   474 -TQIPMKFVVKSILLSAENGIHLKVEKL 500
             :::|:.  .:.::|.::|||:|.:.||
Mouse   483 PSRVPIP--TQQLVLKSKNGIYLHLRKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	111/504 (22%)
Cyp4a29	NP_001093653.1	p450	52..503	CDD:278495	112/508 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910