Protein Alignment Cyp6a23 and Cyp4f17

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001094915.1
• Gene: Cyp4f17 / 208285
• MGIID: 3646233
• Length: 524
• Species: Mus musculus
• Alignment Length: 554
• Identity: 143/554 - (25%)
• Similarity: 229/554 - (41%)
• Gaps: 118/554 - (21%)

  Fly    11 LVSLLLFMAR----------------------RRHGYW--------QRRGIP---------HDVP 36
            ||...||:||                      .||.:|        ...|:.         |||
Mouse    24 LVGASLFLARILTWICAFYDNYCRLRCFPEPPSRHWFWGHMSMVKNNEEGLQLLTERSHQFHDV- 87

  Fly    37 HPIYGNMKDWPKKRHIAMIFRDYYTKYKRSVYP-FAGFYFFFTRSAVITDLELVKRVLIKDFNHF 100
                          |:..|...|  ...|.::| |.|  .....||.:...|:
Mouse    88 --------------HLCWIGPFY--PILRLIHPKFIG--PILQASAAVAPKEM------------ 122

  Fly   101 ENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTT 165
                |||..:...|...|....|:||...||.|||.|....:|.......|....|...:...||
Mouse   123 ----IFYGFLKPWLGDGLLVSAGEKWSRHRHLLTPAFHFDILKPYMKNFNKSVNIMHAKWQRLTT 183

  Fly   166 TGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRA--IIERRYGGL--LDFLI 226
            .|.. .|::::.::..|.|.:.||.|..:.|..::|:.....|.:.:  |::|.:...  ||||.
Mouse   184 KGTA-CLDMLEHISLMTLDSLQNCVFSFDSNCQESPSEYIAAIQELSSLIVKRHHQPFLYLDFLY 247

  Fly   227 F------GFPK-----------LSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSL 274
            :      .|.|           :.|..|..|:.|::::|..|          :|..|..||:|.|
Mouse   248 YCTADGRRFRKACDLVHNFTDAVIRERRRTLSSQNLDEFLKS----------KTKSKTLDFIDVL 302

  Fly   275 IEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVL 339
              :..|::.|..   ||..:|.|:|..|...|.:|:::.:.:.||.||...:.|::.|.|:..:|
Mouse   303 --LLAKDEHGKE---LSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELL 362

  Fly   340 -SKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALG 403
             .:...|..::.:.::.:|...:.|:||.:|.:..::|....|....|.: .|.|||..||...|
Mouse   363 RGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDVVLPDGR-VIPKGTDCVISIFG 426

  Fly   404 IHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKF 468
            :|::||::|:||.:.|.||..|....|....::||..|||||||..|.:.:..|.||..:  .:|
Mouse   427 VHHNPEVWPDPEVYDPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMREMKVALALTL--LRF 489

  Fly   469 SVSTETQIPMKFVVKSILLSAENGIHLKVEKLSK 502
            .|....:.|.:  ...::|.||.|:.|:||.|||
Mouse   490 RVLPGDKEPRR--KPELILRAEGGLWLRVEPLSK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	124/481 (26%)
Cyp4f17	NP_001094915.1	p450	52..515	CDD:365848	131/518 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910