Protein Alignment Cyp6a23 and cyp-13A1

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 133/523 - (25%)
• Similarity: 239/523 - (45%)
• Gaps: 85/523 - (16%)

  Fly    25 YWQRRGIPHDVPHPIYG--------------NMKDWPKKRHIAMIFRDYYTKYKRSVYPFAGFYF 75
            :|:|||:...:..|:.|              ..::|.||      |...|           ||..
 Worm    26 FWRRRGVVGPMGFPVLGVFLNSLDNNFPFPLQCREWTKK------FGKIY-----------GFTE 73

  Fly    76 FFTRSAVITDLELVKRVLIKDFNHF--ENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFT 138
            ...::.||:|.|||..|.:..:::|  ..|.....:.:......||:.:|.:|:.||...:|||:
 Worm    74 GTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTNLFAAQGFRWKRLRAISSPTFS 138

  Fly   139 SGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFG-LNCNSLQNPN 202
            :..::.::..:.....|:.:... |.:.| |:.::::.....:|.||||..|.| .:....:||.
 Worm   139 NSSLRKLYQTVEDSALELLRHIE-KQSAG-GKQIDMLKFYQEFTLDVIGRIAMGQTDSQMFKNPI 201

  Fly   203 AEFVTIGKRAIIERRYGGLLDFLIFG-FP----KLSRRLRLK-LNV---QDVEDFYTSIVRNTID 258
            ...|:    .:.:..:..|  |||.| ||    ::.|::.|| |.|   :.:.:.....:.|.|
 Worm   202 MPIVS----KLFQGNFAKL--FLIGGIFPTFLVEIIRQILLKNLKVGSFRKINEITLDAIHNRI- 259

  Fly   259 YRLRTNEKRH--------DFMDSLIEMYEK------EQAGN-------TEDGLSFNEILAQAFIF 302
             :.|..::::        ||:|..::...:      |..|:       |...|:..||:.|..:|
 Worm   260 -KQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVF 323

  Fly   303 FVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRK 367
            .:|||:|::.::.:|.|.||...:||.:|:.|:|....  |.|.|.:.:.::||:|.|..|.||.
 Worm   324 LIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNRECP--NPEVTIDQLSKLKYMECVFKEALRL 386

  Fly   368 YPV--LAHLTR-MTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERF-TDEAI 427
            ||:  .|:..| |..|...    ...:..||.:.:....:|.||.|: .:.|.|||||: |..:.
 Worm   387 YPLGAFANSRRCMRNTKLG----NMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSD 447

  Fly   428 AARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENG 492
            .......::|||.|||.|||:|...|:..:.|.:::|.:.|....:|:||:|.:.::........
 Worm   448 QIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFETGAKTEIPLKLIGRATTQPESVW 512

  Fly   493 IHL 495
            :||
 Worm   513 MHL 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	127/510 (25%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	123/478 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.760