Protein Alignment Cyp6a23 and cyp-13A5

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 156/555 - (28%)
• Similarity: 271/555 - (48%)
• Gaps: 101/555 - (18%)

  Fly     1 MSLLL---TLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYT- 61
            :|:|:   :.|.||...:...:     :|.|:|:......|.:|.:.:          |:||..
 Worm     3 LSILIAGASFIGLLTYYIWIWS-----FWIRKGVKGPRGFPFFGVIHE----------FQDYENP 52

  Fly    62 ------KYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEID-DP---LSA 116
                  ::.:...|..|......::.::::.|.|..|.:|.|::|..|..  |.|. ||   ..|
 Worm    53 GLLKLGEWTKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGRKT--NPIQGDPNKNKRA 115

  Fly   117 TLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIF------SAKTTTGEGQVLEIV 175
            .|.|.:|.:|:.||...:|||::   ||:..|:..|.|.:.::.      |||     |:.::::
 Worm   116 HLVSAQGHRWKRLRTLSSPTFSN---KNLRKIMSTVEETVVELMRHLDDASAK-----GKAVDLL 172

  Fly   176 DLVARYTADVIGNCAFGLNCNSL--QNPNAEFVTIGKRAIIERRYGGLLDFLIFG-FP---KLSR 234
            |....:|.|:||..|.| ...||  :||....|    :.|.  :.|..|.||:.| ||   .:.|
 Worm   173 DYYQEFTLDIIGRIAMG-QTESLMFRNPMLPKV----KGIF--KDGRKLPFLVSGIFPIAGTMFR 230

  Fly   235 RLRLKL-NVQDVEDFYTSIVRNTIDYRLR---TNEKR--------HDFMD------SLIEMYEKE 281
            ...::. ::|...|. .|.|...::.||.   .:||.        .||:|      :.::.:|:|
 Worm   231 EFFMRFPSIQPAFDI-MSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEE 294

  Fly   282 QA--------GNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNV 338
            .|        ...:..|:|:||:.|.|:|.:||::|::.::.::.|.||...:||.:|:.|::..
 Worm   295 SALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDRE 359

  Fly   339 LSKHNNEFTYEGIKEMKYLEQVVMETLRKYPV--LAHLTR-MTQTDFSPEDPKYFIAKGTTVVIP 400
            ..  |.|.|::.|.::||:|.||.|.||.||:  :.|..: |.:|:.....    |.|||.|.:.
 Worm   360 CP--NPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQ----IEKGTNVQVD 418

  Fly   401 ALGIHYDPEIYPE-PEKFKPERFT--DEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYL 462
            ...:||||:::.| ..:|:|||:.  ||...|:..  :||||.|||.|||:|..:|:..:.|.::
 Worm   419 TWTLHYDPKVWGEDANEFRPERWESGDELFYAKGG--YLPFGMGPRICIGMRLAMMEKKMLLTHI 481

  Fly   463 IRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKV 497
            ::.|.|..||:|:||:|.|..:  .:|...:.||:
 Worm   482 LKKYTFETSTQTEIPLKLVGSA--TTAPRSVMLKL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	146/513 (28%)
cyp-13A5	NP_496112.1	p450	33..514	CDD:278495	147/518 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780