Protein Alignment Cyp6a23 and cyp-13A11

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 145/527 - (27%)
• Similarity: 253/527 - (48%)
• Gaps: 76/527 - (14%)

  Fly     1 MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKR 65
            |.:||.:::.:|.::.:.. ....||:|.|||....:|..|:..|.....:...:....:|....
 Worm     1 MIILLFVVSSVVGIVSYYF-WTWTYWRRCGIPGPQGYPFLGSALDMMDHENPPFLQLKKWTSQYG 64

  Fly    66 SVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEID-DP---LSATLFSIEGQKW 126
            .||   |......|:.||:|..|:..|.:|.:::|..|.:  |.|. ||   ...||||.:|.:|
 Worm    65 KVY---GITEGLLRTLVISDTNLIHEVFVKQYDNFYGRNL--NPIQGDPNREKRVTLFSAQGHRW 124

  Fly   127 RHLRHKLTPTFTSGKMKNMFPIIVKVGEE-MEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCA 190
            :.||....|||:|   .|:..|.|.|.:. :|.:...:..|..|:.:::::....:|.||||..|
 Worm   125 KRLRTIANPTFSS---NNLRKIQVTVEDSALELLRHIEQHTAGGKAIDVLEYFQEFTMDVIGRIA 186

  Fly   191 FGLNCNSL--QNP-------------NAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKL 240
            .| ..:||  :||             .|.|::    .|:....|.::..::|.|..:......::
 Worm   187 MG-QPDSLMFKNPLLPCARDVFGKPRTALFLS----GILFPWIGPMIRKVVFYFTNVFNNPAAQI 246

  Fly   241 NVQDVEDFYTSIVRNTIDYRLR---TNEKR-------HDFMDSLIEMYEKE-QAGNTED------ 288
            ..|         ..|.::.|::   ..||.       .||:|..::....: :..|.||
 Worm   247 MYQ---------TANAVEQRIKQRMAEEKAGIDPGEPQDFIDLFLDAKSDDMELENNEDFTKAGV 302

  Fly   289 ----GLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYE 349
                .|:.:|::.|.|:|.:|||:|::.::.::.:.||.....|.:|:.||:...:  :.|.|::
 Worm   303 KVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEEIDRECA--DPEVTFD 365

  Fly   350 GIKEMKYLEQVVMETLRKYPV--LAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYP 412
            .:.::||:|.|:.||||.||:  ||:..|..:   |.:...|.|.||..::.....:|||..|:.
 Worm   366 QLSKLKYMECVIKETLRMYPLGALANSRRCMR---STKIGNYEIEKGVDILCDTWTLHYDKSIWG 427

  Fly   413 E-PEKFKPERFT--DEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTET 474
            | .|:|||||:.  ||....:..  ::|||.|||.|||:|...|:..:.|::::|.|...|..:|
 Worm   428 EDAEEFKPERWESGDEHFYQKGG--YIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKT 490

  Fly   475 QIPMKFV 481
            |||:|.:
 Worm   491 QIPLKLI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	130/460 (28%)
cyp-13A11	NP_499704.1	CYP3A-like	62..506	CDD:410678	131/465 (28%)