Protein Alignment Cyp6a23 and cyp-13A11

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 148/537 - (27%)
• Similarity: 254/537 - (47%)
• Gaps: 96/537 - (17%)

  Fly     1 MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKR 65
            |.:||.:::.:|.::.:.. ....||:|.|||....:|..|:..|.....:...:....:|....
 Worm     1 MIILLFVVSSVVGIVSYYF-WTWTYWRRCGIPGPQGYPFLGSALDMMDHENPPFLQLKKWTSQYG 64

  Fly    66 SVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEID-DP---LSATLFSIEGQKW 126
            .||   |......|:.||:|..|:..|.:|.:::|..|.:  |.|. ||   ...||||.:|.:|
 Worm    65 KVY---GITEGLLRTLVISDTNLIHEVFVKQYDNFYGRNL--NPIQGDPNREKRVTLFSAQGHRW 124

  Fly   127 RHLRHKLTPTFTSGKMKNMFPIIVKVGEE-MEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCA 190
            :.||....|||:|   .|:..|.|.|.:. :|.:...:..|..|:.:::::....:|.||||..|
 Worm   125 KRLRTIANPTFSS---NNLRKIQVTVEDSALELLRHIEQHTAGGKAIDVLEYFQEFTMDVIGRIA 186

  Fly   191 FGLNCNSL--QNPNAEFVTIGKRAIIERRYGGLLDFL--IFGFPKLSRRLRLKLN---------- 241
            .| ..:||  :||                   ||...  :||.|    |..|.|:
 Worm   187 MG-QPDSLMFKNP-------------------LLPCARDVFGKP----RTALFLSGILFPWIGPM 227

  Fly   242 VQDVEDFYTSI-----------VRNTIDYRLR---TNEKR-------HDFMDSLIEMYEKE-QAG 284
            ::.|..::|::           ..|.::.|::   ..||.       .||:|..::....: :..
 Worm   228 IRKVVFYFTNVFNNPAAQIMYQTANAVEQRIKQRMAEEKAGIDPGEPQDFIDLFLDAKSDDMELE 292

  Fly   285 NTED----------GLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVL 339
            |.||          .|:.:|::.|.|:|.:|||:|::.::.::.:.||.....|.:|:.||:...
 Worm   293 NNEDFTKAGVKVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEEIDREC 357

  Fly   340 SKHNNEFTYEGIKEMKYLEQVVMETLRKYPV--LAHLTRMTQTDFSPEDPKYFIAKGTTVVIPAL 402
            :  :.|.|::.:.::||:|.|:.||||.||:  ||:..|..:   |.:...|.|.||..::....
 Worm   358 A--DPEVTFDQLSKLKYMECVIKETLRMYPLGALANSRRCMR---STKIGNYEIEKGVDILCDTW 417

  Fly   403 GIHYDPEIYPE-PEKFKPERFT--DEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIR 464
            .:|||..|:.| .|:|||||:.  ||....:..  ::|||.|||.|||:|...|:..:.|::::|
 Worm   418 TLHYDKSIWGEDAEEFKPERWESGDEHFYQKGG--YIPFGLGPRQCIGMRLAYMEEKLLLSHILR 480

  Fly   465 GYKFSVSTETQIPMKFV 481
            .|...|..:||||:|.:
 Worm   481 KYTLEVCNKTQIPLKLI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	138/502 (27%)
cyp-13A11	NP_499704.1	p450	31..506	CDD:278495	139/506 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.730