Protein Alignment Cyp6a23 and cyp-25A1

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 149/540 - (27%)
• Similarity: 250/540 - (46%)
• Gaps: 90/540 - (16%)

  Fly     4 LLTLIALLVSLLLF-----MARR-RHGYWQRRGIPHDVPHPIYGNMKDWPKKRH------IAMIF 56
            ||.|.:|::|:..|     :||| |....::.|:....||...||:|...:::.      ....|
 Worm     3 LLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWF 67

  Fly    57 RDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGI--FYNEIDDPLSATLF 119
            .:.:.:|..:.    |.|:....:.||::.:.:|.|.||:|::|.:|.:  .| |.:...::.|.
 Worm    68 NELHEQYGETF----GIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIY-EANQLTASLLM 127

  Fly   120 SIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTAD 184
            :.....|:|.|..:.|.|::||||.|...|....:....|...|.::  ||..:|.|.....|.|
 Worm   128 NSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASS--GQKWDIYDDFQGLTLD 190

  Fly   185 VIGNCAFGLNCNSLQNPNAEFVTIGKRAI--IERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVED 247
            |||.|||.::.|..::.|..|....|:.|  |:.|:..::...:. .|:||             .
 Worm   191 VIGKCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVL-LPELS-------------T 241

  Fly   248 FYTSIVRNT--IDYRLRTNEKRHDFMDSLIEMYEKEQAG-------------NTEDG----LSFN 293
            |:.::.:.|  .|..:       ..::.|..:||:.:.|             |.||.    ::..
 Worm   242 FWKALYKYTPLADAEI-------PLVEGLSNVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQ 299

  Fly   294 EILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLE 358
            |::...|.|.:||:||:||.|.:..|.|:...::|.:|..||  :.:|.|...||:.|..||||:
 Worm   300 EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEI--MEAKENGGLTYDSIHNMKYLD 362

  Fly   359 QVVMETLRKYPVLAH-LTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERF 422
            .|..||||.||.:.| :.|:.:.|.:...  .|..||..||.....:|.:||.:..||:|.||||
 Worm   363 CVYKETLRFYPPVIHFIRRLCREDITIRG--QFYPKGAIVVCLPHTVHRNPENWDSPEEFHPERF 425

  Fly   423 TD-EAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSIL 486
            .: |..::  |..|:|||.|||.|:|:||..|:....:..|:..::..         :|..::.|
 Worm   426 ENWEEKSS--SLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK---------QFEGEADL 479

  Fly   487 LSAENGI----------HLK 496
            :...||:          |||
 Worm   480 IPDCNGVIMRPNDPVRLHLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	135/499 (27%)
cyp-25A1	NP_497775.3	p450	37..496	CDD:278495	135/501 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.860