Protein Alignment Cyp6a23 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 541
• Identity: 127/541 - (23%)
• Similarity: 226/541 - (41%)
• Gaps: 100/541 - (18%)

  Fly     3 LLLTLIALLVSLLLF----MARRRHGYWQRRGIPHDVPHPIYGNMKD------------WPKKRH 51
            |::|::.||  .|||    :||....:      |....|.::|:..:            |.::..
Mouse    22 LMVTVLKLL--SLLFRRQKLARALDSF------PGPPKHWLFGHALEIQKTGGLDKVVTWTEQFP 78

  Fly    52 IA--------MIFRDYY-TKYKRSVY----PFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENR 103
            .|        ::|.:.| ..|.::||    |.|.:.:.|                   |..:..:
Mouse    79 YAHPLWLGQFIVFLNIYEPDYAKAVYSRGDPKAAYVYDF-------------------FLQWIGK 124

  Fly   104 GIFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGE 168
            |             |..:||.||...|..|||.|....:|....|..:....|...:..|.:  |
Mouse   125 G-------------LLVLEGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKAS--E 174

  Fly   169 GQVLEIVDLVARYTADVIGNCAFGLNCNSL-QNPNAEFVTIGKRAII-ERRYGGLL---DFLIFG 228
            .:..:|...|.....|.:..|.||...:.| .:.|:.::.:....:: ::|.....   ||:.:.
Mouse   175 NKSFDIFCDVGHMALDTLMKCTFGKGDSGLSHSDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWL 239

  Fly   229 FPKLSRRLRLKLNVQDVEDFYTSIVR------NTIDYRLRTNEKRH-DFMDSLIEMYEKEQAGNT 286
            .|...|.||.   .|...|....::|      .....:.:..|:|| ||:|.|:       ....
Mouse   240 TPHGRRFLRA---CQIAHDHTDHVIRQRKAALQDEKEQKKLQERRHLDFLDILL-------GARD 294

  Fly   287 EDG--LSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYE 349
            |.|  ||..::.|:...|...|.:|:::.:.:.||.:||....|.:.|.|:..:|...:: |.::
Mouse   295 ESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRDS-FQWD 358

  Fly   350 GIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEP 414
            .:.:|.||...:.|..|.||.:..:.|......:..|.:...| |:.:.:....:|.:..::|:|
Mouse   359 DLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRSLPA-GSLISLHIYALHRNSAVWPDP 422

  Fly   415 EKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMK 479
            |.|.|.||:.|.:..|....::||..|||||||.:|.:.:..|..|..:..::|| ...::||:|
Mouse   423 EVFDPLRFSPENMTGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFS-PDPSKIPIK 486

  Fly   480 FVVKSILLSAENGIHLKVEKL 500
              |..::|.::|||||.::.|
Mouse   487 --VPQLILRSKNGIHLYLKPL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	105/443 (24%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	113/482 (23%)