Protein Alignment Cyp6a23 and Cyp4a14

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 549
• Identity: 133/549 - (24%)
• Similarity: 233/549 - (42%)
• Gaps: 114/549 - (20%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQRRGIPH--DVP-HPIYG-NMKD--------WPKKRHIA- 53
            :.||:|..:|...:.|..||:   |..:.:.|  .:| |.::| ::||        |.:|...|
Mouse    22 AFLLSLFLVLFKAVQFYLRRQ---WLLKTLQHFPCMPSHWLWGHHLKDKELQQILIWVEKFPSAC 83

  Fly    54 -----------MIFRDYYTK--YKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGI 105
                       :::...|.|  ..||....:|.|.||.
Mouse    84 LQCLSGSNIRVLLYDPDYVKVVLGRSDPKASGIYQFFA--------------------------- 121

  Fly   106 FYNEIDDP-LSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVK----VGEEMEKIFSAKTT 165
                   | :...|..:.|:||...|..|||.|....:|....|:..    :.::.||:
Mouse   122 -------PWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKL------ 173

  Fly   166 TGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIF--- 227
            .|:...|||...|:..|.|.:..|||....:...:.|::..|   :|:.:      |:.|.|
Mouse   174 DGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYT---KAVED------LNNLTFFRL 229

  Fly   228 --GFPK------LSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNE-------KRH-DFMDSLIE 276
              .|.|      :|...||..:...:...:|..|......:|:..|       ||| ||:|.|
Mouse   230 RNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDFLDIL-- 292

  Fly   277 MYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSK 341
            ::.:.:..|:   ||..::.|:...|...|.:|:::.:.:..|.||...:.|.:.|.|:.::|.
Mouse   293 LFARMEDRNS---LSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILG- 353

  Fly   342 HNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHY 406
            .....|::.:.:|.|....:.|.||.||.:..::|...:..:..|.: .|.||.|..|...|:|:
Mouse   354 DGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGR-SIPKGITATISIYGLHH 417

  Fly   407 DPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVS 471
            :|..:|.|:.|.|.||..:  ::..|..:|||..|.|||||.:|.:.:..|.:|..:..::. :.
Mouse   418 NPRFWPNPKVFDPSRFAPD--SSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFEL-LP 479

  Fly   472 TETQIPMKFVVKSILLSAENGIHLKVEKL 500
            ..|:||:.  :..::|.::|||||.::||
Mouse   480 DPTRIPVP--IARLVLKSKNGIHLCLKKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	120/506 (24%)
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	120/509 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820