Protein Alignment Cyp6a23 and Cyp4a12b

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 560
• Identity: 130/560 - (23%)
• Similarity: 233/560 - (41%)
• Gaps: 140/560 - (25%)

  Fly     8 IALLVSLLLFMARRRHGYWQRRGI-------PHDVPHPIYGN--MKDWPKKRHIAMIFRDYYTKY 63
            :|.::||||.:.:....|..|:.:       |....|.::|:  :||        ...:|..|:.
Mouse    21 VASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKILKD--------QDLQDILTRI 77

  Fly    64 KRSVYPFAGFYFFFTRSAVIT--DLELVKRVLIKDFNHFENRGIFYNEIDDP------------L 114
            |.  :|.|...:.:.....|.  |.:.:|.:|.:               .||            :
Mouse    78 KN--FPSACPQWLWGSKVRIQVYDPDYMKLILGR---------------SDPKAHGSYRFLAPWI 125

  Fly   115 SATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVK----VGEEMEKIFSAKTTTGEGQVLEIV 175
            ...|..::||.|...|..|||.|....:|....|:..    :.::.|:|      .|:...|||.
Mouse   126 GRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQI------VGQDSTLEIF 184

  Fly   176 DLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKL 240
            ..:...|.|.|..|||. :..|:|              ::|:|                    |.
Mouse   185 QHITLMTLDTIMKCAFS-HEGSVQ--------------LDRKY--------------------KS 214

  Fly   241 NVQDVED----FYTSI----VRNTIDYRLRTN--------EKRHDFMDSLI-----EMYEKEQA- 283
            .:|.|||    |:..:    .:|.|.||:.:|        :..||..|.:|     ::.::|:.
Mouse   215 YIQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHTDQVIKSRRSQLQDEEELE 279

  Fly   284 ----------------GNTEDG--LSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQ 330
                            ...|:|  ||..::.|:...|...|.:|:::.:.:..|.||.:.:.|.:
Mouse   280 KLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQR 344

  Fly   331 LRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGT 395
            .|.||.::|. .....|:..:.:|.|....:.|.||.||.:..::|...:..:..|.: .:.||.
Mouse   345 CRKEIQSLLG-DGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGR-SLPKGI 407

  Fly   396 TVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLA 460
            .|::...|:|::|.::|.||.|.|.||...  ::|.|.::|||..|.|||||.:|.:.:..|.:|
Mouse   408 HVMLSFYGLHHNPTVWPNPEVFDPSRFAPG--SSRHSHSFLPFSGGARNCIGKQFAMNELKVAVA 470

  Fly   461 YLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500
            ..:..::. :...|::|:.  :..|:|.::|||||.::||
Mouse   471 LTLLRFEL-LPDPTRVPIP--IPRIVLKSKNGIHLHLKKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	118/518 (23%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	115/497 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910