Protein Alignment Cyp6a23 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 559
• Identity: 126/559 - (22%)
• Similarity: 229/559 - (40%)
• Gaps: 136/559 - (24%)

  Fly     4 LLTLIALLVSLLLFMARRRHGYWQRRG---IPHDVPHPIYGN--MKDWPKKRHIAMIFRDYYTKY 63
            :|.|:.|||..:.|...|:   |..:.   .|....|..:|:  .|...:.:.|.....::.:.:
Mouse    24 VLGLLLLLVKAVQFYLHRQ---WLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAF 85

  Fly    64 KRSVYPFAGFYFFFTRSAVIT--DLELVKRVLIKDFNHFENRGIFYNEIDDP------------L 114
            .|         :|:...|.:|  |.:.:|.:|.:               .||            :
Mouse    86 PR---------WFWGSKAYLTVYDPDYMKVILGR---------------SDPKANGAYRLLAPWI 126

  Fly   115 SATLFSIEGQKWRHLRHKLTPTF----TSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIV 175
            ...|..:.||.|...|..|||.|    ....:|||...|..:.::.|::      ..:...:||.
Mouse   127 GYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERL------ADQDSSIEIF 185

  Fly   176 DLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKL 240
            ..::..|.|.:..|||. :..|:|              ::..|...|.
Mouse   186 QHISLMTLDTVMKCAFS-HKGSVQ--------------VDGNYRTYLQ----------------- 218

  Fly   241 NVQDVEDFYTSIVRN------TIDYRLRTN--------EKRHDFMDSLIEMYEKEQ---AGNTE- 287
            .:.|:.:.:.|.|||      || |:|.:|        :..||..|.:|:: .|:|   .|..|
Mouse   219 AIGDLNNLFHSRVRNIFHQNDTI-YKLSSNGRLAKQACQLAHDHTDGVIKL-RKDQLQDEGELEK 281

  Fly   288 ---------------------DGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQL 331
                                 |.:|..::.|:...|...|.:|:::.:.:..|.||...|.|.:.
Mouse   282 IKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRC 346

  Fly   332 RAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTT 396
            |.|:.::|. ..:..|::.:.::.|....:.|.||.||.:..:.|...|..:..|.: .:.||..
Mouse   347 REEVQSLLG-DGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-SLPKGVQ 409

  Fly   397 VVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAY 461
            |.:...|:|::|:::|.||.|.|.||..:  :.|.|.::|||..|.|||||.:|.:.:..|.:|.
Mouse   410 VTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVAL 472

  Fly   462 LIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKL 500
            .:..::. :...|::||.  :..::|.::|||:|.::||
Mouse   473 TLLRFEL-LPDPTRVPMP--LARLVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	108/482 (22%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	111/503 (22%)