Protein Alignment Cyp6a23 and Cyp2j6

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_034138.3
• Gene: Cyp2j6 / 13110
• MGIID: 1270148
• Length: 501
• Species: Mus musculus
• Alignment Length: 562
• Identity: 130/562 - (23%)
• Similarity: 211/562 - (37%)
• Gaps: 148/562 - (26%)

  Fly     2 SLLLT----------LIALLVSLLL---FMARRRHGY----WQRRGIPHDVPHPIYGNMKDWPKK 49
            |||.|          |:|.:..|||   |..||...|    |   |:      |..||
Mouse     7 SLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPW---GL------PFVGN------- 55

  Fly    50 RHIAMIFRDYYTKYKRSVYPFA---GFYFFFT----RSAVITDLELVKRVLIKDFNHFENR--GI 105
                 ||:..:.:...|:.|..   |..|...    .|.|||.|.|:|..|.:...:..||  .:
Mouse    56 -----IFQLDFGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSV 115

  Fly   106 FYNEIDDPLSATLFSIEGQKWRHLRHKLTPT---FTSGK-------MKNMFPIIVKVGEEMEKIF 160
            ....|.:. :..:|| .||.|:..|.....|   |..||       .:....::..:.||..|.|
Mouse   116 MQERISNK-NGLIFS-SGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPF 178

  Fly   161 SAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKR-------------- 211
            :...:                    |.|....:.|:         ||.|:|
Mouse   179 NPHFS--------------------INNAVSNIICS---------VTFGERFDYHDSRFQEMLRL 214

  Fly   212 ---------AIIERRYG---GLLDFLIFGFPKLSRRL-RLKLNVQDVEDFYTSIVRNTIDYRLRT 263
                     .:|.:.|.   .::.::.....|:.|.. :|||.|..:.|          |:|...
Mouse   215 LDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMID----------DHRKDW 269

  Fly   264 N-EKRHDFMDSLIEMYEKEQAGNTEDGLSFNE--ILAQAFIFFVAGFETSSTTMGFALYELALDQ 325
            | ::..||:|:.:    ||.....|...||||  ::......|.||.||:|||:.:||..:||..
Mouse   270 NPDEPRDFIDAFL----KEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYP 330

  Fly   326 DIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVL-AHLTRMTQTDFSPEDPKY 389
            ::|::::|||:.|:.: .........:.|.|...|:.|..|...:: .::.|....|.:...  :
Mouse   331 EVQEKVQAEIDRVIGQ-KRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNG--F 392

  Fly   390 FIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEA-IAARPSCTWLPFGEGPRNCIGLRFGLM 453
            .:.|||.|:.....:|.||:.:..|:.|.||.|.:.. ...|.|  :|||..|.|.|:|.:....
Mouse   393 HLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRES--FLPFSMGKRACLGEQLARS 455

  Fly   454 QACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHL 495
            :..:....|::.:.|:.....::..||         .||:.|
Mouse   456 ELFIFFTSLMQKFTFNPPINEKLSPKF---------RNGLTL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	108/476 (23%)
Cyp2j6	NP_034138.3	CYP2J	75..495	CDD:410755	108/473 (23%)