Protein Alignment Cyp6a23 and Cyp2j5

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_034137.1
• Gene: Cyp2j5 / 13109
• MGIID: 1270149
• Length: 501
• Species: Mus musculus
• Alignment Length: 539
• Identity: 129/539 - (23%)
• Similarity: 222/539 - (41%)
• Gaps: 118/539 - (21%)

  Fly     4 LLTLIALLVSLLLF--MARRRH------GYWQRRGIPHDVPHPIYGN-MKDWPKKRHIAMIFRDY 59
            |.||:..:|:.|..  :.|.||      |.|:.         |..|| .:...|:.|  ::.:.:
Mouse    18 LKTLVLAVVTFLFLINILRSRHPKNYPPGPWRL---------PFVGNFFQIDTKQTH--LVLQQF 71

  Fly    60 YTKYKRSVYPFAGFYFFF----TRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSAT--- 117
            ..||        |..|..    :...|::.|.|:|.:    |.|.:..  |.|....|:...
Mouse    72 VKKY--------GNVFSLELGQSPVVVVSGLPLIKEM----FTHLDQN--FVNRFMTPVRERITG 122

  Fly   118 ---LFSIEGQKW---RHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQV----L 172
               |....||.|   |.|.......|..||..    :..::.||...:..|....| ||.    |
Mouse   123 KNGLVVSNGQTWKEQRRLALMALRNFGLGKKS----LEERIQEETHHLVEAIREEG-GQPFNPHL 182

  Fly   173 EIVDLVARYTADVIGNCAFG-----LNC---NSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGF 229
            ::::.|    :::|.:..||     .:|   ..||..:.....:|..|      |.|.:    ||
Mouse   183 KLINAV----SNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSA------GQLYN----GF 233

  Fly   230 PKLSRRL------------RLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDS-LIEMYEKE 281
            |.:.:.|            :|||.|..:      :.::..|:  ..:|.| ||:|: |||| :|:
Mouse   234 PCIMKYLPGPHQKIFRNWGKLKLFVSHI------VKKHEKDW--NPDEPR-DFIDAFLIEM-QKD 288

  Fly   282 QAGNTEDGLSFNE--ILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNN 344
            ....|    ||||  :::.....|:.|.||:|:|:.:||..::...:||:.::|||:.|:. |..
Mouse   289 PDRTT----SFNEENLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIG-HKR 348

  Fly   345 EFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPK---YFIAKGTTVVIPALGIHY 406
            :.:....:.|.|...|:.|..|    :.::..:..:.....|.|   :.:.|||.::.....:|.
Mouse   349 QVSLSDRESMPYTNAVIHEVQR----MGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHR 409

  Fly   407 DPEIYPEPEKFKPERFTDEA-IAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSV 470
            ||:.:..||.|.||.|.:.. ...|.|  :|||..|.|.|:|.:....:..:..:.|::.:.|..
Mouse   410 DPKEWATPEVFNPEHFLENGQFKKRES--FLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKP 472

  Fly   471 STETQIPMKFVVKSILLSA 489
            ....::.:||.:..||..|
Mouse   473 PINEKLSLKFRMGLILSPA 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	112/466 (24%)
Cyp2j5	NP_034137.1	CYP2J	75..495	CDD:410755	113/471 (24%)