Protein Alignment Cyp6a23 and Cyp26a1

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 505
• Identity: 109/505 - (21%)
• Similarity: 184/505 - (36%)
• Gaps: 121/505 - (23%)

  Fly     3 LLLTLIALLVSLLLFMARRRHGYWQRRGI------------PHDVPHPIYGNMKDWPKKRHIAMI 55
            |...|...::.||||:|..:  .|....:            |..:..|.:|..        :.|:
Mouse     7 LASALCTFVLPLLLFLAALK--LWDLYCVSSRDRSCALPLPPGTMGFPFFGET--------LQMV 61

  Fly    56 F-RDYYTKYKRSVYPFAGFYFFFTRSAV-ITDLELVKRVLIKDFNHFENRGIFYNEIDDPLS--- 115
            . |..:.:.||..|.|......|.|..| :...:.|:|:|:.     |:|.:   .:..|.|
Mouse    62 LQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLG-----EHRLV---SVHWPASVRT 118

  Fly   116 ----ATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVL---E 173
                ..|.::.....:..:..:...|:...::...|:|   .||:........:.||..:|   |
Mouse   119 ILGAGCLSNLHDSSHKQRKKVIMQAFSREALQCYVPVI---AEEVSSCLEQWLSCGERGLLVYPE 180

  Fly   174 IVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLD--FLIFGFPKLSRRL 236
            :..|:.|....::..|..|                        ..||..|  .|:..|.:::|.|
Mouse   181 VKRLMFRIAMRILLGCEPG------------------------PAGGGEDEQQLVEAFEEMTRNL 221

  Fly   237 -RLKLNVQDVEDFYTSI-VRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTEDGL--------- 290
             .|.::| .....|..: .||.|..|:..|.:.     .:..:...|..|..:|.|
Mouse   222 FSLPIDV-PFSGLYRGVKARNLIHARIEENIRA-----KIRRLQATEPDGGCKDALQLLIEHSWE 280

  Fly   291 ------------SFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINN--VLSK 341
                        |..|:|       ..|.||:::.....:..|.|...:..::|.||.:  :|.|
Mouse   281 RGERLDMQALKQSSTELL-------FGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCK 338

  Fly   342 HN--NEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGI 404
            .|  |:...|.::::||...|:.||||..|.:....|:....|  |...|.|.||..|:......
Mouse   339 SNQDNKLDMETLEQLKYTGCVIKETLRLNPPVPGGFRVALKTF--ELNGYQIPKGWNVIYSICDT 401

  Fly   405 HYDPEIYPEPEKFKPERFTDEAIAARPS----CTWLPFGEGPRNCIGLRF 450
            |...:|:...|:|.|:||    |...|.    .:::|||.|.|:|:|..|
Mouse   402 HDVADIFTNKEEFNPDRF----IVPHPEDASRFSFIPFGGGLRSCVGKEF 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	100/460 (22%)
Cyp26a1	NP_031837.2	p450	43..491	CDD:299894	101/467 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030