Protein Alignment Cyp6a23 and Cyp4f15

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 545
• Identity: 139/545 - (25%)
• Similarity: 235/545 - (43%)
• Gaps: 87/545 - (15%)

  Fly     7 LIALLVSLLLFMAR-RRHGYWQRRGIPH--DVPHPIYGNMKDWPKKR----HIAMIFRDYYTKYK 64
            |:.||:.....:|| ....|...|...|  |.|.|        ||..    |:.||     |..:
Mouse    25 LLLLLIGASWLLARVLTQTYIFYRTYHHLCDFPQP--------PKWNWFLGHLGMI-----TPTE 76

  Fly    65 R---------SVYPFAGFYFFFTRSAVITDL---ELVKRVLIKDFNHFENRGIFYNEIDDPLSAT 117
            .         :.|| .||..:......|..|   ::::.||....:......:||:.:...|...
Mouse    77 HGLKEVTNLVATYP-QGFMTWLGPIIPIITLCHPDIIRSVLNASASVALKEVVFYSFLKPWLGDG 140

  Fly   118 LFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAK---TTTGEGQVLEIVDLVA 179
            |...:|.||...|..|||.|..    |:....||:..:...|..||   ..:|....|::.:.::
Mouse   141 LLLSDGDKWSSHRRMLTPAFHF----NILKPYVKIFNDSTNIMHAKWQHLASGGSARLDVFENIS 201

  Fly   180 RYTADVIGNCAFGLNCNSLQNPNAEFVT--IGKRAIIERRYGGLLDFL--IFGFPKLSRRLRLKL 240
            ..|.|.:..|.|..:.|..:|| :|:::  :...|::.:||..||..:  ::......||.....
Mouse   202 LMTLDSLQKCVFSFDSNCQENP-SEYISAILELSALVTKRYHQLLLHIDSLYQLTCSGRRFHKAC 265

  Fly   241 NVQDVEDFYTSIVRNTIDYRLRTNEKRH--------------DFMDSLIEMYEKEQAGNTEDG-- 289
            ::  |..|..:::::    |.||...:|              ||:|.|:       ....|||
Mouse   266 HL--VHSFTDAVIQD----RRRTLPSKHEDDVLKAKAKSKTLDFIDVLL-------LSKDEDGKE 317

  Fly   290 LSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVL-SKHNNE-------F 346
            ||..:|.|:|..|...|.:|:::.:.:.||.||...:.|::.|.|:..:| .:.:.|       |
Mouse   318 LSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRDRESTEIECSCAVF 382

  Fly   347 TYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY 411
            ..:.:.::.:|...:.|:||.:|.:..::|....|....|.: .|.||...:|.....|::|.::
Mouse   383 LRDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGR-VIPKGVICIINIFATHHNPTVW 446

  Fly   412 PEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQI 476
            |:||.:.|.||..|.|..|....::||..|||||||..|.:.:..|.||..:  .:|.|..:.:.
Mouse   447 PDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTL--LRFRVLPDDKE 509

  Fly   477 PMKFVVKSILLSAENGIHLKVEKLS 501
            |.:  ...::|.||.|:.|:||.||
Mouse   510 PRR--KPELILRAEGGLWLRVEPLS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	117/459 (25%)
Cyp4f15	NP_598888.1	CYP4F	79..527	CDD:410772	117/471 (25%)