Protein Alignment Cyp6a23 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 536
• Identity: 136/536 - (25%)
• Similarity: 235/536 - (43%)
• Gaps: 82/536 - (15%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQR-RGIPHD------VPHPIYGNMKDWPKKRHIAMIFRD- 58
            ::|:::..:|||    .||:    ||: |.||..      |.|.:|       .|.:.|..|:.
Mouse    28 TILISIFPMLVS----YARK----WQQMRSIPSVARAYPLVGHALY-------MKPNNAEFFQQL 77

  Fly    59 -YYTKYKRSV---------YPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDP 113
             |||:..|.:         .|....|.......::|..:.:            ::...|..:...
Mouse    78 IYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQI------------DKSFLYKFLQPW 130

  Fly   114 LSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQ-VLEIVDL 177
            |...|.:..|.|||..|..|||||....::|...::    .|...|...|......| .......
Mouse   131 LGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVM----NEQANILVNKLEKHVNQEAFNCFFY 191

  Fly   178 VARYTADVIGNCAFGLNCNSLQNPNAEFV-TIGKRA-IIERRYGGL-----LDFLIFGFPKLSRR 235
            :.....|:|...|.|.|..:..|.::|:| |:.:.: :|.||....     |.:|:|...:..:|
Mouse   192 ITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKR 256

  Fly   236 ------------LRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTED 288
                        :..::..:..|:.:|...|..|.    :..||..|:|.|:.:.::|  ||.
Mouse   257 GLKCLHTFTNNVIAERVKERKAEEDWTGAGRGPIP----SKNKRKAFLDLLLSVTDEE--GNR-- 313

  Fly   289 GLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKE 353
             ||..:|..:...|...|.:|::..:.::||.|..:.::|.::..|::.|..:.:...|.|.:|:
Mouse   314 -LSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPVTLEDLKK 377

  Fly   354 MKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFK 418
            :|||:.|:.||||.:|.:....|....|.  |...|.:.|||..:|....:|.||..:|:||:|:
Mouse   378 LKYLDCVIKETLRVFPSVPLFARSLSEDC--EVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFR 440

  Fly   419 PERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVK 483
            ||||..|....|....::||..|||||||.:|.:|:....||.::|  :|.|.:..:.....:..
Mouse   441 PERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILR--QFWVESNQKREELGLAG 503

  Fly   484 SILLSAENGIHLKVEK 499
            .::|...|||.:|:::
Mouse   504 DLILRPNNGIWIKLKR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	113/445 (25%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	118/467 (25%)