Protein Alignment Cyp6a23 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 124/499 - (24%)
• Similarity: 212/499 - (42%)
• Gaps: 72/499 - (14%)

  Fly     4 LLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHP-----IYGNMKDWPKKRHIAMIFRDYYTKY 63
            ||.:|..:|:.|.:.|..::.:.:.    .|:|.|     :.|::....|......:..|.:..:
 Frog    18 LLIIIGAVVAFLAYCAYIKYMHLKY----DDIPGPPRDSFLLGHIPTLSKAEENYSVVHDLFLHW 78

  Fly    64 KRSVYPFAGFYFFFTRSAVITDLELVKRVLI-----KD-------FNHFENRGIFYNEIDDPLSA 116
            .....|..............|..|.||..|:     ||       ||.|..|.:....:.||
 Frog    79 AEIYGPVFKINILHRVMIYSTSPESVKECLMSSKYPKDPYTYNQLFNLFGKRFLGKGLLTDP--- 140

  Fly   117 TLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEG-QVLEIVDLVAR 180
                 :...|.|.|..:.|.|::..:|.|..|..:..|:|.:....|   .:| |.:.:..::.|
 Frog   141 -----DHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEK---ADGHQEVSMHSIINR 197

  Fly   181 YTADVIGNCAFGLNC-----NSLQNPNAEFVTIGKRAIIERRYGGLLDFL----IFGFPKLSRRL 236
            .|.|||...|||::.     |....|||          |.:...|::.::    :..|||....:
 Frog   198 VTLDVITKVAFGMDLGLVEGNKTDFPNA----------ISKVLTGMMRYMQNPYMQYFPKHWAFV 252

  Fly   237 RLKLNVQDVEDFYTSIVRNTIDYRLRT----NEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILA 297
            |   .||:..|......:..|..|.:.    .|...|.:..:::..|.|.|.:       :||:.
 Frog   253 R---EVQESADLLRKTGKECISQRKKAMQNGEELPKDILTKILQCAELENALD-------DEIML 307

  Fly   298 QAFI-FFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVV 361
            ..|| ||:||.||::..:.|.:.||....:|..:||.|::.|:. ...:.:|:.|:.:.|:.||:
 Frog   308 DNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIG-FKRDISYDDIQNLNYMTQVL 371

  Fly   362 METLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEA 426
            .|:||.||.....:|..:.|...|..|  |..|.::......:....:.:.:|.||.||||...|
 Frog   372 KESLRFYPPGPGTSRYLKEDTIFEGIK--IPGGVSITFNTYVMGRMEKFFQDPCKFDPERFHPAA 434

  Fly   427 IAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSV 470
            :  :|...:.||..|||:|:|..|..::|.|.|:.||:.::|.:
 Frog   435 V--KPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFEL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	112/430 (26%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	113/441 (26%)