Protein Alignment Cyp6a23 and cyp3a4.1

DIOPT Version :9

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_002943949.2
• Gene: cyp3a4.1 / 100494419
• XenbaseID: XB-GENE-984218
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 492
• Identity: 163/492 - (33%)
• Similarity: 260/492 - (52%)
• Gaps: 31/492 - (6%)

  Fly     7 LIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDY--YTKYKRSVYP 69
            |:|:|:.|:|......:|.:::.|||...|.|..|...::.|    .||..|.  :.||.|
 Frog    14 LLAVLLVLILLYGIWPYGLFKKMGIPGPTPLPFIGTFLEFRK----GMIQFDIECFKKYGR---- 70

  Fly    70 FAGFYFFFTRSAVITDLELVKRVLIKD-FNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKL 133
            ..|.|........|.|..::|.:|:|: :.:|.||..|  .::.||.:.:...|.::|:.:|..|
 Frog    71 MWGMYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNF--GLNGPLESAITVAEDEQWKRIRSVL 133

  Fly   134 TPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSL 198
            :|||||||:|.||.|:....:.:.|  :.:.:..:.:.....|::..|:.|||.:.:|.:|.:||
 Frog   134 SPTFTSGKLKEMFQIMKDYSDILVK--NVQVSVDKDEPCATKDVIGAYSMDVITSTSFSVNIDSL 196

  Fly   199 QNPNAEFVTIGKRAIIERRYGGLLDFLIFG--FPKLSRRLRLKLNVQDVEDFYTSIVRNTI-DYR 260
            |||:..||...|..:   :.|.|...:||.  ||.| |.:...||:......:|....|.: .:|
 Frog   197 QNPSNPFVIHIKNLL---KTGFLSPVIIFAVIFPFL-RPIFEVLNISFFPKDFTQFFMNAVTSFR 257

  Fly   261 LRTNEKRHDFMDSLIEMY------EKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALY 319
            .:..:..|.....|:::.      |...:.|....|:..||:||:.||..||:||:||.:.:..|
 Frog   258 EKRKKGDHSGRVDLLQLMVDSGTTEGNDSSNQHKALTDAEIMAQSLIFIFAGYETTSTALSYLFY 322

  Fly   320 ELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSP 384
            .||...|:|.:|..||::.|....:. ||:.:.:|:||:.|:.||||.:|....|.|:::.:.
 Frog   323 NLATHPDVQQKLHEEIDSFLPDKASP-TYDILMQMEYLDMVIQETLRLFPPAGRLERVSKQNV-- 384

  Fly   385 EDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLR 449
            |.....|.|||..:|||..:..|||.:||||:|:||||:.|..|.:...|:||||:|||||||||
 Frog   385 EINGVSIPKGTVAMIPAYVLQRDPEYWPEPEEFRPERFSKENRATQTPFTFLPFGDGPRNCIGLR 449

  Fly   450 FGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSIL 486
            |.|:...|.:|.|::.:......||.|||:|....:|
 Frog   450 FALLSMKVAIATLLQNFSVRPCAETLIPMEFSTIGVL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	154/463 (33%)
cyp3a4.1	XP_002943949.2	p450	39..496	CDD:365848	155/467 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	239	1.000	Domainoid score	I2234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm9369
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060