Protein Alignment Cyp6a23 and cyp4b1.3

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: XP_002931492.1
• Gene: cyp4b1.3 / 100487918
• XenbaseID: XB-GENE-980014
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 137/554 - (24%)
• Similarity: 232/554 - (41%)
• Gaps: 118/554 - (21%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQR-----RGIPHDVPHPIYGNMKDWPKKRHIAMIFRD--- 58
            :||..::.||.:..||:.      |:.     :..|....|.:|||          |..||:
 Frog    26 ALLCLILLLLKACGLFIR------WKSLKDALQNFPGPPKHWLYGN----------ANQFRNDGT 74

  Fly    59 -------YYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSA 116
                   :..||.::...:.|.:|   .|.|||:.|..|....:               .||.:.
 Frog    75 DMDRILLWANKYPKAFPLWVGQFF---ASLVITNPEYAKAAFAR---------------SDPKTP 121

  Fly   117 T------------LFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTT--TG 167
            |            |..:.|..|...|..|||.|....:|....:|    .:..|:...|..  :.
 Frog   122 TGYDFLIPWIGKGLLVLSGDTWFQHRRLLTPGFHYDVLKPYAKLI----SDSTKVMLDKWVPFSN 182

  Fly   168 EGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRY------------GG 220
            :|:.:|:...|:..|.|.|..|||..:.| .|..|....|   :|:.:..|            ..
 Frog   183 KGEPVELFHHVSLMTLDSIMKCAFSYHSN-CQTDNDNSYT---KAVYDLSYLTHHRARTFPYHNN 243

  Fly   221 LLDFLI---FGFPKLSRRL---------RLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRH-DFMD 272
            |:.:|.   |.|.|..|..         :.|..:|:.|:|.            :..:||| ||:|
 Frog   244 LIYYLSPHGFLFRKACRIAHQHTDKVIKQRKTLLQNKEEFE------------KVKQKRHPDFLD 296

  Fly   273 SLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINN 337
            .|  :..:::.|.   |||..::.|:...|...|.:|:::.:.:.||.:|...:.|.:.|.||.:
 Frog   297 IL--LCARDENGK---GLSDEDLRAEVDTFMFEGHDTTASGISWILYCMAKYPEHQQKCREEIRD 356

  Fly   338 VLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPAL 402
            ||.: ...|.:|.:.::.|....:.|:||.||.:..::|......:..|.:...| |:.:.|...
 Frog   357 VLGE-KESFEWEDLNKIPYTTMCIKESLRLYPPVPAVSRELNKPITFSDGRSLPA-GSVIFINIF 419

  Fly   403 GIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYK 467
            .||.:|.::.:||.|.|.||:.|..:.|.|..::||..|||||||..|.:.:..|.:|..:..|:
 Frog   420 CIHRNPTVWKDPEVFDPLRFSSENSSKRHSHAFVPFAAGPRNCIGQNFAMNELKVAVALTLNRYE 484

  Fly   468 FSVSTETQIPMKFVVKSILLSAENGIHLKVEKLS 501
            .|... ::.|:|  ...::|.::||||:.::|.|
 Frog   485 LSPDL-SKAPLK--SPQLVLRSKNGIHVYLKKAS 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	116/464 (25%)
cyp4b1.3	XP_002931492.1	CYP4B-like	76..510	CDD:410771	120/481 (25%)