Protein Alignment Cyp6a23 and Cyp2j11

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001004141.2
• Gene: Cyp2j11 / 100066
• MGIID: 2140224
• Length: 504
• Species: Mus musculus
• Alignment Length: 531
• Identity: 119/531 - (22%)
• Similarity: 210/531 - (39%)
• Gaps: 117/531 - (22%)

  Fly     2 SLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPH-----PIYGNMKDWP---KKRHIAMIFRD 58
            :|||||:.||: |..::..||         |.:.|.     |..||:..:.   .:.|:.:  :.
Mouse    20 TLLLTLLTLLL-LADYLKNRR---------PKNYPPGPRRLPFVGNLFQFDLDVSRLHLGI--QP 72

  Fly    59 YYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLI---KDF---------NH-FENRGIFYNEI 110
            :..||...:    ...|.:..|.:|:.|.|:|..:.   ::|         .| |:|.||.::
Mouse    73 FVKKYGNVI----SVNFGYISSVIISGLPLIKEAITGMEQNFLKRPSLAARQHVFKNNGIVFS-- 131

  Fly   111 DDPLSATLFSIEGQKWRHLRH---KLTPTFTSGK-------MKNMFPIIVKVGEEMEKIFSAKTT 165
                       .||.|:..|.   .:...|..||       .:..:.::..:|||
Mouse   132 -----------SGQTWKEQRKFALTILKNFGLGKKSLEQCIQEEAYHLVKAIGEE---------- 175

  Fly   166 TGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFP 230
              :||..:....:.....::|.:..||.......|...|.:.:....|...  ..::..|...||
Mouse   176 --KGQPFDPHFRINNAVGNIICSIIFGERFEYDDNQFQELLKLADEIICSE--ASMMSVLYNVFP 236

  Fly   231 KLSRRL------------RLKLNVQDV-----EDFYTSIVRNTIDYRLRTNEKRHDFMDS-LIEM 277
            .:.:.|            :|||.|..:     ||:..|..|              ||:|: |.||
Mouse   237 SIFKYLPGPQQKLFSNWEKLKLFVSRMMDSHREDWNPSAPR--------------DFIDAFLTEM 287

  Fly   278 YEKEQAGNTEDGLSFNE--ILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLS 340
            .:......|    ||||  ::..|...|.||.||:|.|:.:||..:.::.::|:::.:||:.|:.
Mouse   288 TKYPDKTTT----SFNEENLICTALDLFFAGTETTSNTLRWALLYITVNPEVQEKVHSEIDRVIG 348

  Fly   341 KHNNEFTYEGIKEMKYLEQVVMETLRKYPVL-AHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGI 404
             |....|.:....|.|...|:.|.||...:: .::.|....|.:...  :::.|||.|:|....:
Mouse   349 -HGRHPTLDDQDSMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAG--FYLPKGTMVLINLTDL 410

  Fly   405 HYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFS 469
            |.||:.:..|..|.||.|.:.....:.. ::|||..|.|.|.|.:....:..:....|::.:.|.
Mouse   411 HRDPKEWDTPNVFNPEHFLENGQFKKKE-SFLPFSMGKRACPGEQLASCELFIFFTALMQKFTFK 474

  Fly   470 VSTETQIPMKF 480
            .....:..:||
Mouse   475 SPINEKPSLKF 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	101/457 (22%)
Cyp2j11	NP_001004141.2	cytochrome_P450	77..498	CDD:477761	102/462 (22%)