Protein Alignment Cyp6a23 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 548
• Identity: 130/548 - (23%)
• Similarity: 237/548 - (43%)
• Gaps: 114/548 - (20%)

  Fly     4 LLTLIALLVSLLLFMARRRHGYWQRRGI---PHDVPHPIYGNMK---DWPKKRHIAMIFRDYYTK 62
            :|.|:.|||..:.|...|:   |..:.:   |....|..:|:.:   :...|..::.|      :
Mouse    24 VLGLLLLLVKAVQFYLHRK---WLLKALQQFPSPPFHWFFGHEQFKGEQELKEVVSCI------E 79

  Fly    63 YKRSVYPFAGFYFFFTRSAVIT--DLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQK 125
            :..|.:|    .:|:..:|.:|  |.:.:|.:|.:  :..:..|| |..:...:...|..:.||.
Mouse    80 HFPSAFP----CWFWGSNAYLTVYDPDYMKVILGR--SDPKANGI-YRLLAPWIGYGLLLLNGQP 137

  Fly   126 WRHLRHKLTPTF----TSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVI 186
            |...|..|||.|    ....:|||...|..:.::.|::      .|:...:||...::..|.|.:
Mouse   138 WFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERL------AGQDSSIEIFQHISLMTLDTV 196

  Fly   187 GNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTS 251
            ..|||. :..|:|              ::..|...|.                 .:.|:.:.:.|
Mouse   197 MKCAFS-HKGSVQ--------------VDGNYKTYLQ-----------------AIGDLNNLFHS 229

  Fly   252 IVRN------TIDYRLRTN--------EKRHDFMDSLIEMYEKEQ---AGNTE------------ 287
            .|||      || |||.:|        :..||..|.:|:| .|:|   .|..|
Mouse   230 RVRNIFHQNDTI-YRLSSNGRLAKQACQLAHDHTDGVIKM-RKDQLQDEGELENIKKKRRLDFLD 292

  Fly   288 ----------DGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKH 342
                      |.:|..::.|:...|...|.:|:::.:.:..|.||...:.|.:.|.|:.::|. .
Mouse   293 ILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLG-D 356

  Fly   343 NNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYD 407
            .:..|::.:.::.|....:.|.||.||.:..:.|...|..:..|.: .:.||..|.:...|:|::
Mouse   357 GSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-SLPKGVQVTLSIYGLHHN 420

  Fly   408 PEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVST 472
            |:::|.||.|.|.||..:  :.|.|.::|||..|.|||||.:|.:.:..|.:|..:..::. :..
Mouse   421 PKVWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFEL-LPD 482

  Fly   473 ETQIPMKFVVKSILLSAENGIHLKVEKL 500
            .|::|..  :..|:|.::|||:|.::||
Mouse   483 PTRVPEP--LARIVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	112/470 (24%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	116/492 (24%)