DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pcf11 and PCFS4

DIOPT Version :9

Sequence 1:	NP_610999.4	Gene:	Pcf11 / 36658	FlyBaseID:	FBgn0264962	Length:	1953	Species:	Drosophila melanogaster
Sequence 2:	NP_680598.2	Gene:	PCFS4 / 825827	AraportID:	AT4G04885	Length:	808	Species:	Arabidopsis thaliana

Alignment Length:	973	Identity:	187/973 - (19%)
Similarity:	321/973 - (32%)	Gaps:	306/973 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NYRDDERRIGEEYLSS------------LQDLNCNSKPLINMLTMLAEENINYAHIIVKVVEYYI 59
            |.|:||...|||.|..            |.:|..||||:|..||::|.|...:...|...:...|
plant    45 NQREDEFGGGEEVLPPSMDEIVQLYEVVLGELTFNSKPIITDLTIIAGEQREHGEGIANAICTRI 109

  Fly    60 SQVAPEFKLPILYLIDSIVKNVKSSYVQLFGQCIVNIFLHAFESVQHSQSQVLEKVRERMYALRQ 124
            .:...|.|||.|||:||||||:...|.:.|...:..:|..|:.....|       :...|..|..
plant   110 LEAPVEQKLPSLYLLDSIVKNIGRDYGRYFSSRLPEVFCLAYRQAHPS-------LHPSMRHLFG 167

  Fly   125 TWNEVFPPSKMYALDVKVK--RLDNNWPITAKQPTNKIHVNPAIHVNPDFLKPGLVPGMPGNPTI 187
            ||:.||||..:..:|::::  ...|...:.|.:|:....   .|||||.:|
plant   168 TWSSVFPPPVLRKIDMQLQLSSAANQSSVGASEPSQPTR---GIHVNPKYL-------------- 215

  Fly   188 TSDMEEILQAKTRELLELKKRKLELELEQTKKHLEEQERQLTQTTDAMVGAPIIMPAPTPAAICP 252
                                |:||
plant   216 --------------------RRLE----------------------------------------- 219

  Fly   253 PITDPGIAVHNQRAPGVMGNVGPVMHNMPVAPQLFANKPKVHPVNPALLNSVRQRDPRLARQMHA 317
                |..|.:|.|.                                  :||        :.:::.
plant   220 ----PSAAENNLRG----------------------------------INS--------SARVYG 238

  Fly   318 ASSHPAAPARND--PRLEAKSS-SSQKSSRSRSKSPVRNSSSRSGKSGSSSHSSSSSR----KRS 375
            .:|   ....||  .:||:.|| ||.....:|..:...|.|:::...|....:|....    :|.
plant   239 QNS---LGGYNDFEDQLESPSSLSSTPDGFTRRSNDGANPSNQAFNYGMGRATSRDDEHMEWRRK 300

  Fly   376 ESKSSTTSSSSSSSDVRHKGVTAS---SSNQPTVKRSGKITSKDSDRYVRNGSPLGSAKRKSSS- 436
            |:...........:.:...||..|   :.|:|....:|        .:.:..:|..:.:.:...
plant   301 ENLGQGNDHERPRALIDAYGVDTSKHVTINKPIRDMNG--------MHSKMVTPWQNTEEEEFDW 357

  Fly   437 PSSSPSKSKRSTSHKSSSSRGKTSSLRSRSR----SPVFMDVDLRTGVRSKSPESRAVAPSSLPL 497
            ...||:..:........||.....|:|:|.|    |...:|.|::.||..:..|:.:::.:   .
plant   358 EDMSPTLDRSRAGEFLRSSVPALGSVRARPRVGNTSDFHLDSDIKNGVSHQLRENWSLSQN---Y 419

  Fly   498 AGASLPASAKAPKDLEKPTFQILEPGHPPAPPSPPIIDVSSMDIDLRRPKTPPPPTFDSVDSLDQ 562
            ...|.....:|.|||:                    :..||:.:.....:...|| |||:..::.
plant   420 PHTSNRVDTRAGKDLK--------------------VLASSVGLVSSNSEFGAPP-FDSIQDVNS 463

  Fly   563 K------DTTSGHISSTIIQASGASN-----------ASPSGASTSKLPAKVSFKIQKQFNKLEK 610
            :      |.|..|:|     |.|.::           |:|..|.:::|..|..::.:.|.::...
plant   464 RFGRALPDGTWPHLS-----ARGPNSLPVPSAHLHHLANPGNAMSNRLQGKPLYRPENQVSQSHL 523

  Fly   611 STANLSTVSMLNSNPTTSGTPAASLVRQSSPSPSSSSISSQGNVSDALQLSINKLLQVQGGAGEK 675
            :........::|..|::|.         .:|.|..|.::...:.......:|...|.:|||....
plant   524 NDMTQQNQMLVNYLPSSSA---------MAPRPMQSLLTHVSHGYPPHGSTIRPSLSIQGGEAMH 579

  Fly   676 RPADALPPHIDGEEQPPQQKRSKSAKLDALFGSEDVDLRREILVVKPGVIVVEDDSMD------E 734
            ..:..:...|....|||      ......|.||          ::..|:|.:.:....      |
plant   580 PLSSGVLSQIGASNQPP------GGAFSGLIGS----------LMAQGLISLNNQPAGQGPLGLE 628

  Fly   735 CDVD--KPTKKS------GSPPKKATLEELRAKLAN----------SARIQNKQGKSDKSRDQAV 781
            .|.|  |...:|      |..|::.|...||.|...          :....:|..|.:.||...|
plant   629 FDADMLKIRNESAISALYGDLPRQCTTCGLRFKCQEEHSKHMDWHVTKNRMSKNHKQNPSRKWFV 693

  Fly   782 SQRL-------------------KQLAELKVNDDSQEAHDEKVRTILSQAQEMYENNGMNQEQYK 827
            |..:                   :...|.|.::|.....||. :|..:...|.:|      :.|.
plant   694 SASMWLSGAEALGAEAVPGFLPTEPTTEKKDDEDMAVPADED-QTSCALCGEPFE------DFYS 751

  Fly   828 DLVQKVV---AINENSKIKESRRRDNDLERNAARDAVLRKRIPKLKGNENHSAGSPHTDGSPR 887
            |..::.:   |:..|:. :||   ..|::::.....|..|..|:       |.|....:||.|
plant   752 DETEEWMYKGAVYMNAP-EES---TTDMDKSQLGPIVHAKCRPE-------SNGGDMEEGSQR 803

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcf11	NP_610999.4	CID	17..134	CDD:239621	42/128 (33%)
		Siah-Interact_N	187..255	CDD:286164	3/67 (4%)
		Stathmin	736..>839	CDD:279209	27/142 (19%)
PCFS4	NP_680598.2	CID_Pcf11	66..186	CDD:340779	40/126 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2071
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3055
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15921
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000