Protein Alignment Ercc1 and FAAP24

DIOPT Version :9

• Sequence 1: NP_477468.1
• Gene: Ercc1 / 36654
• FlyBaseID: FBgn0028434
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_689479.1
• Gene: FAAP24 / 91442
• HGNCID: 28467
• Length: 215
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 52/215 - (24%)
• Similarity: 91/215 - (42%)
• Gaps: 41/215 - (19%)

  Fly    63 VLVHSKQRGNPILKSIL-NVPLEFRDDIVPDYVVGRTSCVLYLSLKYHNLNPDYICQRLKALGKM 126
            ::.:.|.||:.:.:.:. .:.|.|.|.:.||:.:....|:||::      ..|.:.      |..
Human    19 IVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVT------EADLVA------GNG 71

  Fly   127 YELRVLLVQVDTPEPNNALKSL-----TRIS----------LLADLTMML---AWNAEEAGKIIE 173
            |..|::.|:     .:|.||.:     ||:|          .:.||.|:|   |...|.:..:|:
Human    72 YRKRLVRVR-----NSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQ 131

  Fly   174 TYKQFEKRP---PDLIMERVESNPHQKLLAALTNIKPVNKTDAAALLHTFGNLGNIINASEERLS 235
            ..::..|.|   |.|..:|........||..:..|..|.|..|..||..|.::..:.|||...|.
Human   132 LVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELE 196

  Fly   236 QVMGLGPRKAKKLYKTLQEP 255
            ||  :|...|::::....:|
Human   197 QV--VGQAVAQQIHAFFTQP 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ercc1	NP_477468.1	RAD10	1..257	CDD:227566	52/215 (24%)
		DUF1556	<26..70	CDD:284914	1/6 (17%)
		Rad10	62..176	CDD:281785	29/131 (22%)
		HHH_5	202..254	CDD:291205	15/51 (29%)
FAAP24	NP_689479.1	PND	11..134	CDD:375443	29/131 (22%)
		RuvA domain 2-like	160..215		17/57 (30%)
		HHH_2	166..215	CDD:372333	16/51 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810