Protein Alignment SMC2 and sbcC

DIOPT Version :9

• Sequence 1: NP_610995.1
• Gene: SMC2 / 36653
• FlyBaseID: FBgn0027783
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_414931.1
• Gene: sbcC / 949076
• ECOCYCID: EG10927
• Length: 1048
• Species: Escherichia coli
• Alignment Length: 1077
• Identity: 205/1077 - (19%)
• Similarity: 390/1077 - (36%)
• Gaps: 273/1077 - (25%)

  Fly    29 AITGLNGSGKSNILDSICFVL--GISNLQNVRASALQDLVYKNGQAGITKATVTI------VFDN 85
            ||||..|:||:.:||:||..|  ....|.||..|. .||:.::....:.:....:      .|.:
E. coli    34 AITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQ-NDLMTRDTAECLAEVEFEVKGEAYRAFWS 97

  Fly    86 TNPAQ-CPQGYEKCREISVTRQVVVGGKNKFLINGKLVQNKKVQDFFCSIQLNVN---------N 140
            .|.|: .|.|..:...:.:.|          ..:||::.: ||:|   .::|...         .
E. coli    98 QNRARNQPDGNLQVPRVELAR----------CADGKILAD-KVKD---KLELTATLTGLDYGRFT 148

  Fly   141 PNFLIMQGKIQQVLNMKPKEVLSMVEEAAGTSQYK-------TKRDATKTLIEKKETKVRETKVL 198
            .:.|:.||:....||.||||...::||..||..|.       .:..:.:|.:||.:.:.....:|
E. coli   149 RSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLL 213

  Fly   199 LDEEVLPKLVKLR----QERSAYQEYQKICRDIDFLIR-IHISAKYLKQCETLKTVEANEHKIED 258
            ..|:|......|:    :|:......|:..:.:::|.| ..:..:..::.:.|:...|.|.|.:.
E. coli   214 TPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQP 278

  Fly   259 RIANCK-ATHAKNL----AEVESIENSVKEMQQQIDAEMGGSIKNLETQLSAKRALEATATGSLK 318
            ::|... |..|:||    ..:.....::..::|||:        .:.|:|.:..||.|:......
E. coli   279 QLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIE--------EVNTRLQSTMALRASIRHHAA 335

  Fly   319 AAQGTIQQDEKKI--------RMASKNIEDDERALAKKEADMAKVQGEFESLKEADARDSKAYED 375
            .....:||.::.:        |....|.|.     |...|..::...:.|.|::...:.:.| |.
E. coli   336 KQSAELQQQQQSLNTWLQEHDRFRQWNNEP-----AGWRAQFSQQTSDREHLRQWQQQLTHA-EQ 394

  Fly   376 AQKKLEAVSQGLSTNE-------NGEASTLQEQLIVAKEQFSEAQTTIKTSEIELRHTRGVLKQR 433
            ....|.|::..|:.:|       :.|...|::.|:....|....|..:...::.:::......||
E. coli   395 KLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQR 459

  Fly   434 EGETQTNDAAY-VKDKKLHDQLVV-----EIKNLERQLQSLD------------------YEG-- 472
            ..........| .|.::|.|...:     .||.||.|...|.                  |:.
E. coli   460 NAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALE 524

  Fly   473 ------------GHFEKLKQR----RNDLHMRKRDLKRELDRCNASRYDLQ-------------- 507
                        ...:||.:.    |..|....:.|:|:.:...:.|.|.|
E. coli   525 PGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLN 589

  Fly   508 -----YQDPEPNFD--------------RRKVRGLVGK------LFQVKDMQNSMALVQTAGGSL 547
                 ..|.:|..|              |.:::|.:..      .:|.:..|....|:.|..|..
E. coli   590 ITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYA 654

  Fly   548 YSYVTDDDVTS---------KKILQRGN----LQRRV-TLIPINKI--QSGSLNRNVVEYAQNKV 596
            .:...:|:..|         :...||.|    ||.|: .|.||.:.  ||..|     .:.:..|
E. coli   655 LTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDEL-----PHCEETV 714

  Fly   597 GAENVQWAMSLIDYDRYYEPVMKFCFG-----GTLICKDLIVAK-----QISYDPRINCRSVTLE 651
            ..||             :..|.:.|..     .||..:|::.|:     |..:|       ..|:
E. coli   715 VLEN-------------WRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFD-------TALQ 759

  Fly   652 GDVVDPHGTVSGGAAPKGANVLEELHAIKQ-IEKEYREIDSEIAQVEKQIASIE----NQALAFN 711
            ..|.|......  ||......|.:|..:|| :|.:.|:..:.:.|..:.:|..:    :..||..
E. coli   760 ASVFDDQQAFL--AALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALT 822

  Fly   712 KMKENLDLRQHELTMCENRLAQTTFQQNQAEIEEMRERVKTLEQQIIDSREKQKTSQAKIVDIEA 776
            ...|.:   |.||.....:|.:.|..|.     |:|:::|    |..|:|::|:|...:|..:..
E. coli   823 VTVEQI---QQELAQTHQKLRENTTSQG-----EIRQQLK----QDADNRQQQQTLMQQIAQMTQ 875

  Fly   777 KLADAKGYRERELNA------------------ATNEIKVTKQRAEKSRANWKKREQEFETLQLE 823
            ::.| .||    ||:                  ..|.:.:..|:..:....:..:.:..|.|::|
E. coli   876 QVED-WGY----LNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVE 935

  Fly   824 ITELQKSIETAKKQHQEM---------------IDNLEKFKAELDALKVNSSSAASEVTELEQAI 873
            :.:..::  .|.:..:.:               :.:|...|..:|:|.::......:...|:.|:
E. coli   936 VVDTWQA--DAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTAL 998

  Fly   874 KEQKDKLRDQNKEMRNQLVKKEKMLKENQEIELEVKK 910
             :..|.|....|.:  .::...:.:||...::::|||
E. coli   999 -DALDALNASGKTI--GVISHVEAMKERIPVQIKVKK 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC2	NP_610995.1	Smc	1..1168	CDD:224117	205/1077 (19%)
		ABC_SMC2_euk	1..>170	CDD:213240	41/158 (26%)
		SMC_hinge	520..637	CDD:214944	29/148 (20%)
		V_Alix_like	690..933	CDD:187408	45/258 (17%)
		P-loop_NTPase	<1073..1167	CDD:304359
sbcC	NP_414931.1	PRK10246	1..1048	CDD:182330	205/1077 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I342
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003760
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	2	2.050