Protein Alignment SMC2 and mscK

DIOPT Version :9

• Sequence 1: NP_610995.1
• Gene: SMC2 / 36653
• FlyBaseID: FBgn0027783
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_414998.1
• Gene: mscK / 945132
• ECOCYCID: G6255
• Length: 1120
• Species: Escherichia coli
• Alignment Length: 492
• Identity: 94/492 - (19%)
• Similarity: 195/492 - (39%)
• Gaps: 113/492 - (22%)

  Fly   706 QALAFNKMKENLDL--------------RQHELTMCENRLAQTTFQQNQA---EIEEMRERVKTL 753
            |..||.:...|.||              :|.:|: .:::|.|.......|   :|:.::|....|
E. coli    28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLS-AQDKLVQQDLTDTLATLDKIDRIKEETVQL 91

  Fly   754 EQQIIDSREKQKTSQAKIVDIEAKLADAKGYRERELNAATNEIKVTKQRAEKSRANWKKREQEFE 818
            .|::.::.||.:.:.|.:    ..|:|.....|.....:|..::..:.|..::..:.:..:.:..
E. coli    92 RQKVAEAPEKMRQATAAL----TALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLA 152

  Fly   819 TLQLEITELQKSIETAKKQHQEMIDNLEKFKAELDALKVNSSSAASEVTELEQAIK-------EQ 876
            :...::..||...|..:.........|::.::.||...|..::.......|.||.:       :|
E. coli   153 SYNSQLVSLQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQ 217

  Fly   877 KDKLRDQNKEMRNQLVKKEKMLKENQ---EIELEVKKKENEQKKISSDAKEAKKRMEALEA---- 934
            :.|..:.|..:::.|.|:...:..|.   |.:|::.::....|:::...|.|::.:...||
E. coli   218 QRKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDEAARIQ 282

  Fly   935 KYPWIPEEKNCFGMKNTRYDYSKEDPHEAGNKLAKMQEK-KDKMERTLNMNAIMVLDREEENFKE 998
            ..|.:.:|.......:.|...:.|:    ||:|.:...| |:.:||.|         :.|.|.||
E. coli   283 ANPLVKQELEINQQLSQRLITATEN----GNQLMQQNIKVKNWLERAL---------QSERNIKE 334

  Fly   999 TERRRNIVAMDKEK--IKKIIVKMD------EEEQDQLNKAAT------EVNTNFSGIFSSLLPG 1049
            .      :|:.|..  :.:|:.:..      :|.::..|:.|.      |||.....:|.|
E. coli   335 Q------IAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQS---- 389

  Fly  1050 AEA---KLNPVHTN--------GCLTGLEIKVGFNGIWKESLGELSG--GQKSLVALSLVLAMLK 1101
             :|   ||...|||        ..|..::::       :|.|.:|:.  |.:.::|::|
E. coli   390 -DAFVNKLEEGHTNEVNSEVHDALLQVVDMR-------RELLDQLNKQLGNQLMMAINL------ 440

  Fly  1102 FSPAPLYILDEVDAALDMSHTQNIGSMLKQH--FTNS 1136
                      :::....||.::|:.|:|.|.  :.||
E. coli   441 ----------QINQQQLMSVSKNLKSILTQQIFWVNS 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC2	NP_610995.1	Smc	1..1168	CDD:224117	94/492 (19%)
		ABC_SMC2_euk	1..>170	CDD:213240
		SMC_hinge	520..637	CDD:214944
		V_Alix_like	690..933	CDD:187408	44/253 (17%)
		P-loop_NTPase	<1073..1167	CDD:304359	14/68 (21%)
mscK	NP_414998.1	PRK11281	7..1120	CDD:236892	94/492 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1196
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	0.900