Protein Alignment SMC2 and TTN8

DIOPT Version :10

• Sequence 1: NP_610995.1
• Gene: SMC2 / 36653
• FlyBaseID: FBgn0027783
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_001319748.1
• Gene: TTN8 / 824632
• AraportID: AT3G54670
• Length: 1218
• Species: Arabidopsis thaliana
• Alignment Length: 1299
• Identity: 287/1299 - (22%)
• Similarity: 543/1299 - (41%)
• Gaps: 263/1299 - (20%)

  Fly     3 VKKLVLDGFKSYGRRTEIEGFDPEFTAITGLNGSGKSNILDSICFVLGISNLQNVRASALQDLVY 67
            :.:|.::.|||| :..::.|...:||||.|.|||||||::|:|.||||:...| :|.|.|:||:|
plant    11 ILQLEMENFKSY-KGHQLVGPFKDFTAIIGPNGSGKSNLMDAISFVLGVRTGQ-LRGSQLKDLIY 73

  Fly    68 -----KNGQAGITKATVTIVFDNTNPAQCPQGYEKCREISVTRQVVVGGKNKFLINGKLVQNKKV 127
                 ...|.| .||.|.:|:      |...|.    |:..||.:...|.:::.|:.::|...:.
plant    74 AFDDRDKEQRG-RKAFVRLVY------QMDDGV----ELRFTRSITSAGGSEYRIDNRVVNLDEY 127

  Fly   128 QDFFCSIQLNVNNPNFLIMQGKIQQVLNMKPKEVLSMVEEAAGTSQYKTKRDATKTLIEKKETKV 192
            .....|:.:.|...|||:.||.::.:.:..|||:..::||.:|:.:.|.:.:.    :|:|:...
plant   128 NGKLRSLGILVKARNFLVFQGDVESIASKNPKELTGLLEEISGSEELKKEYEG----LEEKKASA 188

  Fly   193 RETKVLL--------DEEVLPKLVK---------------LRQERSAYQEY------QKICRDID 228
            .|...|:        :|:.|.|..|               |::||..:|.|      :|...|:|
plant   189 EEKAALIYQKKKTIGNEKKLKKAQKEEAEKHLRLQEELKALKRERFLWQLYNIENDIEKANEDVD 253

  Fly   229 FLIRIHISAKYLKQCETLKTVEANEHKIEDRIANCKATHAKNLAEVESIENSVKEMQQQID---- 289
                        .:....|.|.....|.|......|...||.|.|:...|..:.|...::.
plant   254 ------------SEKSNRKDVMRELEKFEREAGKRKVEQAKYLKEIAQREKKIAEKSSKLGKIQP 306

  Fly   290 ---------AEMGGSIKNLETQLSAKRALEATATGSLKAAQGTIQQDEKKIRMASKNIEDDERAL 345
                     |.:...|:.....:..::..:...:..::..|.:|::..||:.:.:|..:|....|
plant   307 ELLRFKEEIARIKAKIETNRKDVDKRKKEKGKHSKEIEQMQKSIKELNKKMELFNKKRQDSSGKL 371

  Fly   346 ------------AKKEADM--AKVQGEFESLKEADARDSKAYEDAQKKLEAVSQGLSTNENGEAS 396
                        .|:||.|  .|::.|.|.|:    |..:...:|.:.||...|.|...:|
plant   372 PMLDSQLQDYFRLKEEAGMKTIKLRDEHEVLE----RQRRTDLEALRNLEENYQQLINRKN---- 428

  Fly   397 TLQEQLIVAKEQFSEAQTTIKTSEIELRHTRGVLKQREGETQTNDAAYVKDKKLHDQLVVEIKNL 461
            .|.||:    ::|.:.|..|:||..:.::....||.   |.:.....:|..::...:|...|..|
plant   429 DLDEQI----KRFKDRQGEIETSSSKYKNETTSLKT---ELRALQEKHVNAREASAKLKTRIAEL 486

  Fly   462 ERQLQSLD---YEGGH-------FEKLKQRRNDLHMRKRDLKRELDRCNASRYDLQYQDPEPNFD 516
            |.||..|.   ||...       .|.||:....:|.|..||.|.    |..:|:|
plant   487 EDQLSDLTAERYENERDSRLTQAVESLKRLFQGVHGRMTDLCRP----NRKKYNL---------- 537

  Fly   517 RRKVRGLVGKLFQVKDMQNSMALVQTAGGSLYSYVTDDDVTSKKILQRGNLQR--RVTLIPINKI 579
                                 |:....|..:.:.|.:|:.|.|..::....||  .:|.||:..:
plant   538 ---------------------AVTVAMGRFMDAVVVEDENTGKDCIKYLKEQRLPPMTFIPLQSV 581

  Fly   580 QSGSLNRNVVEYAQNKVGAENVQWAMSLIDYDRYYEPVMKFCFGGTLICKDLIVAKQISYDPRIN 644
            :.    :.|.|..:|..|...:  ...:|.:|...|..:.:..|.||:|.:|..||.:|:... .
plant   582 RV----KQVFERLRNLGGTAKL--VFDVIQFDPELEKAVLYAVGNTLVCDELEEAKVLSWSGE-R 639

  Fly   645 CRSVTLEGDVVDPHGTVSGGAAP--------------KG--------ANVLEELHAIKQIEKEYR 687
            .:.||::|.::...||::||.:.              :|        ...||.:.:|::::.:..
plant   640 FKVVTVDGILLTKAGTMTGGTSGGMEAKSNKWDDKKIEGLKKNKEDFEQQLENIGSIREMQMKES 704

  Fly   688 EIDSEIAQVEKQI--ASIENQALAFNKMKENL-DLRQHELTMCE--NRL------AQTTFQQNQA 741
            ||..:|:.:||:|  |.||.:::     |:.| .|.|.|..:.|  :|:      |:|...:.:.
plant   705 EISGKISGLEKKIQYAEIEKKSI-----KDKLPQLEQEERNIIEEIDRIKPELSKARTEVDKRKT 764

  Fly   742 EIEEMRERVKTLEQQIIDSREKQKTSQAKIVDIEAKLADAKGYRERELNAATNE----IKVTKQR 802
            |:.::.:|:    .:|:|...|..:....:.:|..       |.|.:|..|..|    ::::.|.
plant   765 EMNKLEKRM----NEIVDRIYKDFSQSVGVPNIRV-------YEETQLKTAEKEAEERLELSNQL 818

  Fly   803 A--------EKSR---ANWKKREQEFETLQLEITELQKSIETAKKQHQEMIDNLEKFKAELDALK 856
            |        |::|   :..:|.|....:|:.::..:||::...|:...::.:.:..:|.|::..|
plant   819 AKLKYQLEYEQNRDVGSRIRKIESSISSLETDLEGIQKTMSERKETAVKITNEINNWKKEMEECK 883

  Fly   857 VNSSSAASEVTELEQAIKEQKDKLRDQNKEMRNQLVKKEKMLKENQEIELEVKKKENEQKKISSD 921
            ..|.....|:.:.::...:....:...|:::.::..:.|:::.:.||| .|..:.|:....:.||
plant   884 QKSEEYEKEILDWKKQASQATTSITKLNRQIHSKETQIEQLISQKQEI-TEKCELEHITLPVLSD 947

  Fly   922 AKEAKKRMEALEAKYPWIPEEKNCFGMKNTRYDYSKEDPHEAGNKL-----AKMQEKKDKMERTL 981
            |      ||..::..|.       |........|.:|....|..|:     .|::.|..::|||.
plant   948 A------MEEDDSDGPQ-------FDFSELGRAYLQERRPSAREKVEAEFRQKIESKTSEIERTA 999

  Fly   982 -NMNAIMVLDREEENFKETERRRNIVAMDKEKIKKIIVKMDEEEQDQLNKAATEVNTNFSGIFSS 1045
             |:.|:...:..:|..|:..:.......:::::......:.::..:...:|...:.:|...|:..
plant  1000 PNLRALDQYEAIQEKEKQVSQEFEAARKEEKQVADAFNTVKQKRYELFMEAFNHIASNIDKIYKQ 1064

  Fly  1046 LLP------GAEAKLNPVHTNG-CLTGLEIKVGFNGIWKESLGELSGGQKSLVALSLVLAMLKFS 1103
            |..      |..|.||..:.:. .|.|::............:.:||||:|::.||:|:.::..:.
plant  1065 LTKSNTHPLGGTAYLNLENEDDPFLHGIKYTTMPPTKRFRDMEQLSGGEKTVAALALLFSIHSYR 1129

  Fly  1104 PAPLYILDEVDAALDMSHTQNIGSMLKQHFTNS-------------QFLIVSLKDGLFNHANVL 1154
            |:|.:||||||||||..:...:...::.....:             |.:::||||..::.|..|
plant  1130 PSPFFILDEVDAALDNLNVAKVAKFIRSKSCQAARDNQDAEDGNGFQSIVISLKDSFYDKAEAL 1193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC2	NP_610995.1	SMC_N	2..1162	CDD:481474	287/1299 (22%)
TTN8	NP_001319748.1	SMC_N	11..1196	CDD:481474	287/1299 (22%)